Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   NQZ84_RS02150 Genome accession   NZ_CP102094
Coordinates   430667..431308 (+) Length   213 a.a.
NCBI ID   WP_002937025.1    Uniprot ID   A0A0H3MTV8
Organism   Streptococcus suis strain 12RC1     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 425667..436308
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ84_RS02130 (NQZ84_02130) - 425967..426704 (+) 738 WP_004194145.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  NQZ84_RS02135 (NQZ84_02135) pknB 426704..428362 (+) 1659 Protein_385 Stk1 family PASTA domain-containing Ser/Thr kinase -
  NQZ84_RS10680 - 428483..428698 (+) 216 Protein_386 serine/threonine protein kinase -
  NQZ84_RS02140 (NQZ84_02140) liaF 429023..429682 (+) 660 WP_223375661.1 cell wall-active antibiotics response protein LiaF -
  NQZ84_RS02145 (NQZ84_02145) - 429679..430695 (+) 1017 WP_024401576.1 sensor histidine kinase -
  NQZ84_RS02150 (NQZ84_02150) vraR 430667..431308 (+) 642 WP_002937025.1 response regulator transcription factor Regulator
  NQZ84_RS02155 (NQZ84_02155) - 431358..432758 (+) 1401 WP_044768661.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  NQZ84_RS02160 (NQZ84_02160) - 432760..433131 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  NQZ84_RS02165 (NQZ84_02165) cysK 433157..434083 (-) 927 WP_002937015.1 cysteine synthase A -
  NQZ84_RS02170 (NQZ84_02170) - 434173..434805 (-) 633 WP_015646510.1 YigZ family protein -
  NQZ84_RS02175 (NQZ84_02175) comFA/cflA 434862..436154 (+) 1293 WP_257049611.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23790.36 Da        Isoelectric Point: 4.8970

>NTDB_id=614675 NQZ84_RS02150 WP_002937025.1 430667..431308(+) (vraR) [Streptococcus suis strain 12RC1]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=614675 NQZ84_RS02150 WP_002937025.1 430667..431308(+) (vraR) [Streptococcus suis strain 12RC1]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTTCGCCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCGTTAGAGGTTAAACCCGATGTTGTAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACCCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTATCTAGATAATGAGAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCCGCCATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGACAATCAACGAATTGCAGATGAGTCCTTCATTTCCCTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAAGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MTV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413