Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   SCRE_RS05005 Genome accession   NC_022236
Coordinates   1004458..1005690 (-) Length   410 a.a.
NCBI ID   WP_006267807.1    Uniprot ID   F9P6J5
Organism   Streptococcus constellatus subsp. pharyngis C232     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 999458..1010690
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCRE_RS04985 (SCRE_0982) - 999904..1001640 (-) 1737 WP_006267937.1 ABC transporter ATP-binding protein -
  SCRE_RS04990 (SCRE_0983) - 1001854..1002651 (-) 798 WP_020997828.1 formate/nitrite transporter family protein -
  SCRE_RS04995 (SCRE_0984) - 1002826..1003533 (-) 708 WP_020997829.1 glucosaminidase domain-containing protein -
  SCRE_RS05000 (SCRE_0985) yihA 1003858..1004445 (-) 588 WP_020997830.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  SCRE_RS05005 (SCRE_0986) clpX 1004458..1005690 (-) 1233 WP_006267807.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  SCRE_RS10400 (SCRE_0987) - 1005744..1005917 (-) 174 WP_003024903.1 hypothetical protein -
  SCRE_RS05015 (SCRE_0988) - 1005917..1006429 (-) 513 WP_020997831.1 dihydrofolate reductase -
  SCRE_RS05025 (SCRE_0989) - 1006714..1007553 (-) 840 WP_006267886.1 thymidylate synthase -
  SCRE_RS05030 (SCRE_0990) - 1007639..1008856 (-) 1218 WP_006267929.1 chloride channel protein -
  SCRE_RS05035 (SCRE_0991) - 1008872..1009135 (-) 264 WP_006267865.1 chorismate mutase -
  SCRE_RS05040 (SCRE_0992) - 1009174..1010016 (-) 843 WP_020997832.1 hypothetical protein -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45672.12 Da        Isoelectric Point: 4.3966

>NTDB_id=61467 SCRE_RS05005 WP_006267807.1 1004458..1005690(-) (clpX) [Streptococcus constellatus subsp. pharyngis C232]
MPTNRTSEMMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPQELLNILNHYVIGQDR
AKRALAVAVYNHYKRINFHDNREEEDDVELQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKIIGFGQNNKAIDENSSYMQEIISEDIQKFGLIPELIGRLPVFAALEPLTVEDLVR
ILREPKNALVKQYQTLLSYDDVTLEFDDDALQEIANKAIEHKTGARGLRSIIEETMMDVMFEVPSQENVKLVRITKEAVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=61467 SCRE_RS05005 WP_006267807.1 1004458..1005690(-) (clpX) [Streptococcus constellatus subsp. pharyngis C232]
ATGCCTACAAATCGTACGAGCGAAATGATGGTTTATTGTTCTTTTTGTGGTAAAAGTCAAGAAGAAGTTCAAAAAATTAT
TGCAGGAAATAATGCATTTATTTGTAACGAATGTGTGGAATTAGCACAAGAAATTATTAGAGAAGAATTAGCAGAAGAAG
TATTAGCAGACTTGTCGGAAGTACCAAAACCACAAGAATTGCTTAACATTTTAAATCACTATGTAATAGGGCAAGATCGT
GCAAAGCGAGCGCTGGCTGTTGCTGTATACAATCACTATAAACGTATCAATTTTCACGATAATCGTGAAGAAGAGGATGA
TGTCGAATTACAAAAATCCAATATTCTTATGATTGGTCCAACCGGTTCTGGTAAGACTTTTCTTGCTCAAACTTTAGCGA
AAAGTCTAAATGTTCCCTTTGCGATTGCAGATGCGACAGCTTTGACGGAAGCTGGCTATGTGGGGGAAGATGTTGAAAAC
ATTCTCTTAAAACTCTTGCAAGCTGCAGATTTTAATATTGAGCGTGCAGAACGTGGCATTATCTATGTAGATGAGATTGA
CAAAATTGCAAAGAAAAGCGAAAACGTCTCTATTACTCGTGATGTTTCTGGTGAAGGCGTTCAGCAAGCTTTGCTTAAAA
TCATTGAAGGGACTGTAGCTAGTGTACCTCCTCAAGGTGGTCGCAAACATCCACAGCAAGAAATGATTCAAGTGGATACT
AAGAATATTCTTTTTATCGTTGGTGGTGCTTTTGACGGAATTGAAGAAATTGTCAAACAACGTCTAGGTGAAAAGATTAT
TGGTTTTGGTCAAAATAACAAAGCTATTGATGAAAATAGTTCTTATATGCAAGAAATTATTTCCGAAGATATTCAAAAAT
TTGGACTCATCCCCGAATTGATTGGTCGTTTACCAGTGTTTGCTGCGCTTGAGCCTTTGACAGTTGAGGATTTGGTACGA
ATTCTTCGTGAGCCTAAGAATGCTTTAGTGAAACAATATCAAACGCTTCTTTCTTATGACGATGTTACATTAGAGTTTGA
TGATGATGCTCTCCAAGAGATTGCTAACAAAGCTATTGAACACAAGACAGGTGCTCGTGGCTTGCGCTCGATTATCGAAG
AAACCATGATGGATGTCATGTTTGAAGTACCAAGTCAAGAAAATGTGAAGTTAGTGCGGATTACCAAGGAAGCAGTTGAT
GGAACAGATAAACCGATTTTAGAAACAGCTTAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F9P6J5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.098

100

0.861
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.458

98.049

0.573

Multiple sequence alignment