Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   NPS17_RS02325 Genome accession   NZ_CP101985
Coordinates   480181..480822 (+) Length   213 a.a.
NCBI ID   WP_002263036.1    Uniprot ID   -
Organism   Streptococcus mutans strain COCC33-14R     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 475181..485822
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS17_RS02305 (NPS17_02305) - 475458..476201 (+) 744 WP_002263040.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  NPS17_RS02310 (NPS17_02310) pknB 476198..478048 (+) 1851 WP_002263039.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  NPS17_RS02315 (NPS17_02315) liaF 478492..479187 (+) 696 WP_002263038.1 cell wall-active antibiotics response protein LiaF -
  NPS17_RS02320 (NPS17_02320) - 479184..480188 (+) 1005 WP_002263037.1 sensor histidine kinase -
  NPS17_RS02325 (NPS17_02325) vraR 480181..480822 (+) 642 WP_002263036.1 response regulator transcription factor Regulator
  NPS17_RS02330 (NPS17_02330) - 480866..482281 (+) 1416 WP_002263035.1 Cof-type HAD-IIB family hydrolase -
  NPS17_RS02335 (NPS17_02335) - 482265..482651 (+) 387 WP_002268943.1 S1 RNA-binding domain-containing protein -
  NPS17_RS02340 (NPS17_02340) - 482730..483506 (-) 777 WP_082999678.1 glycyl-radical enzyme activating protein -
  NPS17_RS02345 (NPS17_02345) - 483637..484383 (+) 747 WP_002263032.1 DeoR/GlpR family DNA-binding transcription regulator -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23824.40 Da        Isoelectric Point: 4.8864

>NTDB_id=613707 NPS17_RS02325 WP_002263036.1 480181..480822(+) (vraR) [Streptococcus mutans strain COCC33-14R]
MSKTKVILVDDHEMVRLGLKSFLNLQDNVEVIGEASNGRQGIDLALKLKPDVVVMDLVMPEMDGVEATLELLKDWKEAKI
LVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIQKVAKGDLAIETEVDKKIKDHHNNPDLHEDLTARERDILALLA
KGYDNQTIADELFISLKTVKTHVSNILSKLQVDDRTQAVVYAFQHHLVPQDEN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=613707 NPS17_RS02325 WP_002263036.1 480181..480822(+) (vraR) [Streptococcus mutans strain COCC33-14R]
ATGAGTAAAACAAAAGTTATACTGGTTGATGATCATGAAATGGTTCGATTGGGTTTGAAAAGTTTTCTTAATTTACAAGA
TAATGTAGAAGTTATCGGTGAGGCTAGCAATGGCCGTCAAGGTATTGACTTGGCTTTAAAATTAAAACCAGACGTTGTTG
TCATGGACTTGGTTATGCCAGAAATGGATGGTGTAGAAGCCACTCTTGAACTTCTAAAAGATTGGAAAGAAGCCAAAATT
CTAGTTTTAACCAGTTATTTAGATAACGAAAAAATTTATCCTGTCATTGAAGCAGGTGCTAAAGGTTATATGTTGAAAAC
TTCCAGTGCAGCTGAAATTTTGAATGCCATTCAAAAAGTAGCTAAGGGAGATTTAGCGATTGAAACAGAAGTTGATAAGA
AAATCAAGGATCACCATAATAATCCTGATTTGCATGAAGATTTAACAGCGCGTGAACGAGACATTTTGGCTTTACTTGCT
AAGGGTTATGATAACCAAACGATTGCTGATGAGCTTTTCATTTCTTTGAAGACTGTCAAAACACATGTTTCTAATATCTT
ATCGAAATTACAAGTTGATGATCGGACCCAAGCCGTTGTCTATGCTTTTCAGCATCATTTAGTGCCACAGGACGAAAATT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.22

96.244

0.493
  degU Bacillus subtilis subsp. subtilis str. 168

35.398

100

0.376