Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   NPS18_RS08805 Genome accession   NZ_CP101984
Coordinates   1786713..1787726 (+) Length   337 a.a.
NCBI ID   WP_002263739.1    Uniprot ID   Q8DSA7
Organism   Streptococcus mutans strain UA-159     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1781713..1792726
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS18_RS08780 (NPS18_08780) - 1781905..1782090 (-) 186 WP_002263346.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  NPS18_RS08790 (NPS18_08790) - 1783667..1783828 (-) 162 WP_002263734.1 Blp family class II bacteriocin -
  NPS18_RS08795 (NPS18_08795) - 1783873..1784127 (-) 255 WP_002263733.1 Blp family class II bacteriocin -
  NPS18_RS08800 (NPS18_08800) - 1784584..1786700 (+) 2117 Protein_1688 peptide cleavage/export ABC transporter -
  NPS18_RS08805 (NPS18_08805) comB 1786713..1787726 (+) 1014 WP_002263739.1 HlyD family efflux transporter periplasmic adaptor subunit Regulator
  NPS18_RS08810 (NPS18_08810) - 1787988..1788131 (-) 144 WP_002263740.1 hypothetical protein -
  NPS18_RS08815 (NPS18_08815) - 1788198..1788350 (-) 153 WP_002263741.1 hypothetical protein -
  NPS18_RS08820 (NPS18_08820) - 1788423..1789445 (-) 1023 WP_002263742.1 thioredoxin family protein -
  NPS18_RS08825 (NPS18_08825) - 1789931..1790119 (-) 189 WP_002263743.1 Blp family class II bacteriocin -
  NPS18_RS08830 (NPS18_08830) - 1790283..1790495 (-) 213 WP_002263744.1 Blp family class II bacteriocin -
  NPS18_RS08835 (NPS18_08835) - 1790900..1791064 (-) 165 WP_002265308.1 hypothetical protein -
  NPS18_RS08840 (NPS18_08840) - 1791504..1791716 (+) 213 Protein_1696 IS3 family transposase -
  NPS18_RS08845 (NPS18_08845) - 1791839..1792243 (-) 405 WP_002263912.1 hypothetical protein -

Sequence

Protein


Download         Length: 337 a.a.        Molecular weight: 38498.13 Da        Isoelectric Point: 10.7202

>NTDB_id=613655 NPS18_RS08805 WP_002263739.1 1786713..1787726(+) (comB) [Streptococcus mutans strain UA-159]
MNPNLFKSAEFYRRRYHNFATVLIIPLVCLLVFLFIFLLFAKKEVTVLSDGEISPIKVIDVIQSKSDYPISENNLTDNHA
VKKRDVLIQYVNPAANTRQGGNNQNQNQSQNKQNKNQQQNNKNQKNGNQGQKNQNQNQNKKDQKNNNQSQQNKQGQKKTN
QSQNQQNKNQNKNQSQNKQNGNQNQNNWNQNNQNDKVTASQDGVIHTNPKYEGENLIPRGTEIAQLYPDINKTRQVLITY
YVSSKDVTRLKQGQKTHLALTKVGNDQISIRGKINSIASAATTTKKGNVFKVTAKAKVSKKDSQTIKYGLQGKTITVVEK
KTFFDYYKDKLLNKNQK

Nucleotide


Download         Length: 1014 bp        

>NTDB_id=613655 NPS18_RS08805 WP_002263739.1 1786713..1787726(+) (comB) [Streptococcus mutans strain UA-159]
ATGAACCCAAATTTATTTAAAAGCGCTGAATTCTACCGAAGACGCTATCATAATTTTGCTACAGTTCTTATTATTCCTTT
GGTTTGTTTACTTGTATTTTTATTTATCTTTCTATTATTTGCTAAAAAAGAGGTCACTGTCTTGTCTGATGGCGAGATCT
CTCCCATTAAAGTAATTGATGTTATTCAATCTAAAAGTGATTATCCCATTTCTGAAAATAATTTAACAGATAATCACGCC
GTTAAAAAAAGGGATGTTCTCATCCAATATGTTAATCCAGCAGCAAATACAAGACAGGGCGGAAATAATCAGAATCAAAA
TCAATCTCAAAACAAGCAAAATAAGAATCAGCAGCAAAACAATAAGAATCAAAAAAACGGCAATCAAGGTCAAAAAAATC
AAAATCAGAACCAAAATAAAAAGGATCAGAAAAACAATAACCAATCTCAGCAAAACAAGCAAGGACAAAAGAAAACTAAT
CAATCCCAAAATCAGCAGAATAAGAATCAAAATAAAAACCAATCTCAAAACAAACAAAATGGGAATCAAAACCAAAATAA
CTGGAATCAGAATAATCAAAATGATAAAGTCACAGCCAGCCAAGATGGTGTTATCCATACCAACCCCAAATATGAAGGTG
AAAACTTAATTCCTCGGGGGACTGAAATCGCACAGCTCTATCCAGATATTAACAAAACAAGACAAGTTCTGATCACTTAT
TACGTCTCCTCTAAAGATGTCACCCGCCTCAAACAAGGCCAAAAGACTCATCTTGCTTTAACCAAGGTAGGAAATGATCA
AATTTCCATTAGAGGAAAAATTAATAGTATCGCTTCAGCTGCTACAACGACGAAAAAAGGCAATGTTTTTAAAGTGACAG
CTAAAGCAAAAGTTTCTAAAAAAGACAGCCAAACCATTAAATACGGCCTCCAGGGTAAAACCATCACAGTTGTTGAAAAA
AAGACTTTCTTTGATTATTATAAAGATAAACTGTTAAATAAAAATCAAAAATAA

Domains

Predicted by InterProScan.

HlyD family secretion protein ()

(196-309)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DSA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mutans UA159

100

100

1
  comB/nlmE Streptococcus mutans UA159

50.299

99.11

0.499