Detailed information NTG0613222

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: NP436_RS14335
• Genome accession: NZ_CP101932
• Coordinates: 2648413..2649675 (-)
• Length: 420 a.a.
• NCBI ID: WP_003229613.1
• Uniprot ID: A0ABU0V489
• Organism: Bacillus subtilis subsp. natto strain BGSC 27E1
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2643413..2654675

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NP436_RS14320 (NP436_14320)	yihA	2643512..2644099 (-)	588	WP_003229621.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
NP436_RS14325 (NP436_14325)	lon	2644096..2646420 (-)	2325	WP_014480468.1	endopeptidase La	-
NP436_RS14330 (NP436_14330)	lonB	2646601..2648259 (-)	1659	WP_004398923.1	ATP-dependent protease LonB	-
NP436_RS14335 (NP436_14335)	clpX	2648413..2649675 (-)	1263	WP_003229613.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
NP436_RS14340 (NP436_14340)	tig	2649947..2651221 (-)	1275	WP_014480469.1	trigger factor	-
NP436_RS14345 (NP436_14345)	ddcA	2651449..2652453 (-)	1005	WP_014480470.1	DNA damage checkpoint antagonist DdcA	-
NP436_RS14350 (NP436_14350)	leuD	2652573..2653172 (-)	600	WP_014480472.1	3-isopropylmalate dehydratase small subunit	-
NP436_RS14355 (NP436_14355)	leuC	2653185..2654603 (-)	1419	WP_003229604.1	3-isopropylmalate dehydratase large subunit	-

Sequence

Protein

• Length: 420 a.a.
• Molecular weight: 46350.22 Da
• Isoelectric Point: 4.5879

>NTDB_id=613222 NP436_RS14335 WP_003229613.1 2648413..2649675(-) (clpX) [Bacillus subtilis subsp. natto strain BGSC 27E1]
MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGTEEEVEFKDVPKPQEIREILNEYVIGQDQ
AKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILL
KLIQAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNI
LFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLEKEDLLSKVLPEDLLRFGLIPEFIGRLPVIASLEKLDEEALVAIL
TKPKNALVKQFKKMLELDNVELEFEEEALSEIAKKAIERKTGARGLRSIIEGIMLDVMFELPSRDDIEKCVITGATVTHG
EPPRLLLKDGTEVSQDKTSA

Nucleotide

• Length: 1263 bp

>NTDB_id=613222 NP436_RS14335 WP_003229613.1 2648413..2649675(-) (clpX) [Bacillus subtilis subsp. natto strain BGSC 27E1]
ATGTTTAAATTTAACGAGGAAAAAGGACAATTAAAATGCTCGTTCTGTGGAAAAACACAAGATCAGGTTCGTAAGCTTGT
AGCTGGACCTGGTGTATATATATGTGACGAATGTATCGAACTCTGCACTGAAATTGTAGAGGAAGAACTCGGAACAGAAG
AAGAAGTAGAATTTAAAGACGTACCAAAGCCTCAGGAAATTCGCGAAATTTTGAATGAATATGTCATCGGCCAAGATCAA
GCGAAGAAATCACTTGCTGTTGCTGTGTATAACCACTATAAGCGCATTAACTCCAACAGCAAAGTTGATGATGTTGAGCT
TTCAAAAAGTAATATTTCATTAATCGGCCCTACGGGAAGCGGTAAAACCCTTCTGGCGCAAACATTGGCTCGCATTTTAA
ATGTGCCGTTTGCGATTGCGGACGCTACATCTTTGACTGAAGCTGGATACGTGGGTGAAGATGTAGAGAATATTCTCTTG
AAGCTCATCCAAGCTGCTGATTATGATGTGGAAAAAGCCGAAAAAGGCATTATCTATATTGATGAAATCGATAAAGTGGC
TAGAAAATCTGAAAACCCGTCTATCACACGTGATGTGTCAGGTGAGGGTGTACAGCAGGCATTGCTTAAAATTCTTGAGG
GTACAGTGGCAAGCGTACCGCCTCAAGGTGGACGTAAGCATCCTCATCAAGAATTCATTCAAATTGACACAACAAATATT
TTGTTCATTTGCGGCGGAGCTTTCGATGGTATCGAACAAATCATCAAACGCCGTTTAGGCCAAAAAGTGATTGGATTCGG
TGCCGACAATAAAGCTGCTGATCTTGAGAAAGAAGATCTTCTTTCAAAAGTGCTTCCAGAAGATTTGCTCCGTTTCGGGT
TAATTCCTGAATTTATCGGACGTCTTCCGGTTATTGCAAGCCTTGAAAAGCTTGACGAAGAAGCATTGGTTGCGATCTTA
ACAAAACCGAAAAACGCTCTTGTTAAGCAATTCAAGAAAATGCTTGAGCTTGACAACGTTGAGCTTGAGTTTGAAGAAGA
AGCGCTTTCTGAAATTGCTAAAAAAGCAATTGAACGCAAGACTGGAGCACGCGGACTCCGTTCTATCATTGAAGGCATCA
TGCTTGATGTGATGTTTGAGCTGCCTTCTCGTGATGACATTGAAAAATGTGTAATCACCGGGGCAACTGTGACACACGGA
GAGCCTCCTCGCCTCTTATTAAAAGACGGCACTGAGGTAAGCCAAGATAAAACATCTGCATAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (109-305)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (311-389)

• ClpX C4-type zinc finger (zf-C4_ClpX) (11-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	68.01	94.524	0.643
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	60.506	94.048	0.569