Detailed information NTG0613164

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: NP436_RS06850
• Genome accession: NZ_CP101932
• Coordinates: 1304004..1306103 (+)
• Length: 699 a.a.
• NCBI ID: WP_017695065.1
• Uniprot ID: -
• Organism: Bacillus subtilis subsp. natto strain BGSC 27E1
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1299004..1311103

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NP436_RS06815 (NP436_06815)	ykvS	1299022..1299207 (+)	186	WP_003232446.1	YkvS family protein	-
NP436_RS06820 (NP436_06820)	ykvR	1299329..1299619 (-)	291	WP_014479639.1	YkvR family protein	-
NP436_RS06825 (NP436_06825)	queF	1299940..1300437 (-)	498	WP_003218613.1	preQ(1) synthase	-
NP436_RS06830 (NP436_06830)	queE	1300455..1301186 (-)	732	WP_014479638.1	7-carboxy-7-deazaguanine synthase QueE	-
NP436_RS06835 (NP436_06835)	queD	1301179..1301628 (-)	450	WP_003232462.1	6-carboxytetrahydropterin synthase QueD	-
NP436_RS06840 (NP436_06840)	queC	1301621..1302280 (-)	660	WP_014479637.1	7-cyano-7-deazaguanine synthase QueC	-
NP436_RS06845 (NP436_06845)	-	1302593..1303636 (-)	1044	WP_014479636.1	hypothetical protein	-
NP436_RS06850 (NP436_06850)	clpE	1304004..1306103 (+)	2100	WP_017695065.1	ATP-dependent protease ATP-binding subunit ClpE	Regulator
NP436_RS06855 (NP436_06855)	motA	1306488..1307297 (+)	810	WP_014479634.1	flagellar motor stator protein MotA	-
NP436_RS06860 (NP436_06860)	motB	1307272..1308054 (+)	783	WP_014479633.1	flagellar motor protein MotB	-
NP436_RS06865 (NP436_06865)	mhqR	1308094..1308531 (-)	438	WP_003232475.1	MarR family transcriptional regulator MhqR	-
NP436_RS06870 (NP436_06870)	kinD	1308724..1310244 (+)	1521	WP_031600444.1	sporulation kinase KinD	-
NP436_RS06875 (NP436_06875)	-	1310272..1310702 (-)	431	Protein_1289	hypothetical protein	-
NP436_RS06880 (NP436_06880)	spo0E	1310788..1311045 (-)	258	WP_003218598.1	aspartyl-phosphate phosphatase Spo0E	-

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77805.88 Da
• Isoelectric Point: 5.1326

>NTDB_id=613164 NP436_RS06850 WP_017695065.1 1304004..1306103(+) (clpE) [Bacillus subtilis subsp. natto strain BGSC 27E1]
MRCQHCHQNEATIRLNMQINSVHKQMVLCETCYNELTRKPSMSMGPQSFGFPFEQAFQPKEKSAAKQSGKKGLLDELAQN
ITNGAKAGLIDPVIGRDDEVARVIEILNRRNKNNPVLIGEPGVGKTAIAEGLALKIAEGDVPNKLKNKELYLLDVASLVA
NTGIRGQFEERMKQLITELKERKNVILFIDEIHLLVGAGSAEGSMDAGNILKPALARGELQVIGATTLKEYRQIEKDAAL
ERRFQPVMVQEPSIEQAILILQGIKDKYEAYHGVTFSDEAIKACVTLSSRYIQDRHLPDKAIDLLDEAGSKANLLIDELN
DEDAAERLTAIEAEKTKALEEENYELAAKLRDEELALEKKLNSSSAHTAVTVEAEHIQEIVEQKTGIPVGKLQADEQTKM
KELEAKLHERVIGQEAAVQKVAKAVRRSRAGLKSKNRPVGSFLFVGPTGVGKTELSKTLADELFGTKDAIIRLDMSEYME
KHAVSKIIGSPPGYVGHEEAGQLTEKVRRNPYSIVLLDEIEKAHPDVQHMFLQIMEDGRLTDSQGRTVSFKDTVIIMTSN
AGAGEKQTKVGFQSDDSVIEEQTLIDSLSMFFKPEFLNRFDSIIEFRSLEKEHLVKIVSLLLGELEETLAERGISLNVTD
EAKEKIAELGYHPSFGARPLRRTIQEWVEDEMTDLLLDNGEITSFHVILEDDKIKVQAK

Nucleotide

• Length: 2100 bp

>NTDB_id=613164 NP436_RS06850 WP_017695065.1 1304004..1306103(+) (clpE) [Bacillus subtilis subsp. natto strain BGSC 27E1]
ATGCGTTGTCAACATTGTCATCAAAACGAGGCGACGATTCGCCTTAACATGCAAATAAATTCCGTTCATAAACAGATGGT
TCTTTGTGAAACTTGCTATAACGAACTGACCCGTAAACCTTCAATGAGTATGGGTCCTCAATCTTTCGGATTTCCGTTTG
AACAGGCATTCCAGCCGAAAGAAAAGAGCGCAGCAAAACAAAGCGGAAAAAAAGGGCTGCTTGATGAGCTGGCTCAAAAT
ATTACAAACGGTGCAAAAGCCGGTCTCATTGACCCCGTCATCGGCCGTGATGATGAAGTGGCGCGAGTGATCGAAATTCT
AAACCGCCGGAACAAAAACAATCCGGTTCTTATTGGTGAGCCGGGTGTAGGGAAAACTGCCATCGCTGAAGGGCTCGCTT
TAAAAATTGCTGAAGGTGATGTTCCAAACAAACTGAAAAACAAAGAGCTATATTTGCTTGATGTTGCATCCCTTGTTGCA
AACACAGGGATCAGAGGCCAATTTGAGGAGAGAATGAAACAGCTGATCACTGAGCTGAAGGAACGAAAAAATGTCATTCT
GTTCATTGATGAAATTCACCTTCTCGTCGGCGCAGGCTCTGCAGAAGGATCAATGGACGCCGGCAACATTCTCAAACCGG
CCCTAGCCAGAGGCGAACTGCAAGTCATTGGTGCGACAACACTGAAAGAATATCGTCAAATCGAAAAAGATGCCGCGCTG
GAAAGACGTTTTCAGCCTGTCATGGTGCAGGAGCCTTCAATTGAACAGGCTATCCTCATTCTGCAAGGGATTAAAGACAA
ATACGAGGCATACCATGGCGTAACATTCAGTGATGAAGCAATCAAAGCATGTGTCACTTTATCATCCCGCTACATTCAGG
ACAGACACCTGCCGGATAAAGCAATTGATTTATTAGATGAAGCAGGTTCAAAAGCCAACCTGTTAATTGATGAACTGAAT
GATGAGGATGCCGCTGAACGCTTAACTGCAATTGAAGCCGAAAAAACAAAAGCCCTGGAAGAAGAAAATTACGAACTTGC
GGCAAAACTCCGTGATGAAGAACTCGCATTGGAGAAAAAACTGAACAGCTCCTCCGCTCATACCGCTGTCACTGTGGAAG
CTGAGCACATTCAGGAAATTGTTGAACAAAAAACAGGCATCCCTGTCGGCAAACTGCAGGCAGACGAACAAACGAAAATG
AAAGAACTCGAAGCAAAACTTCATGAACGCGTGATTGGACAAGAAGCCGCTGTTCAAAAAGTGGCAAAGGCGGTAAGACG
AAGCCGCGCCGGTTTAAAATCCAAAAACAGACCAGTCGGCTCCTTCCTCTTCGTCGGTCCTACCGGCGTAGGGAAAACAG
AGCTTTCTAAAACACTGGCAGATGAATTATTCGGCACAAAAGACGCTATTATCCGACTCGATATGAGCGAATACATGGAG
AAACACGCCGTATCTAAAATTATCGGTTCACCGCCTGGATATGTCGGCCATGAGGAAGCTGGACAATTAACTGAGAAAGT
GCGCCGCAATCCTTACAGCATTGTGTTGCTGGATGAGATTGAAAAAGCACACCCAGACGTTCAGCATATGTTCCTGCAAA
TTATGGAGGATGGCCGTCTGACAGACAGCCAAGGCAGAACTGTAAGCTTCAAAGACACAGTGATCATCATGACAAGTAAT
GCGGGTGCTGGTGAGAAACAAACGAAAGTCGGTTTCCAATCAGATGACAGTGTCATCGAAGAACAAACATTGATTGATTC
ACTGAGCATGTTCTTTAAACCTGAGTTCCTCAACCGTTTTGACAGCATTATTGAGTTCCGCTCATTGGAAAAAGAACATC
TTGTCAAAATCGTCAGCCTTCTTCTTGGAGAACTTGAAGAAACATTGGCTGAACGGGGCATTAGCTTGAATGTGACAGAT
GAAGCGAAAGAAAAAATCGCTGAGCTGGGCTACCACCCTTCATTCGGTGCACGTCCGCTTAGAAGAACCATCCAAGAATG
GGTTGAGGATGAAATGACCGATCTGCTGCTTGATAATGGCGAGATCACAAGTTTTCACGTGATTTTAGAAGATGATAAAA
TCAAAGTGCAAGCGAAATAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (253-352)

• AAA domain (Cdc48 subfamily) (AAA_2) (437-603)

• ATPase family associated with various cellular activities (AAA) (AAA) (116-247)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (609-679)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	56.528	100	0.601
clpC	Lactococcus lactis subsp. cremoris KW2	56.284	100	0.589
clpE	Streptococcus pneumoniae TIGR4	54.924	100	0.567
clpE	Streptococcus pneumoniae Rx1	54.924	100	0.567
clpE	Streptococcus pneumoniae D39	54.924	100	0.567
clpE	Streptococcus pneumoniae R6	54.924	100	0.567
clpC	Bacillus subtilis subsp. subtilis str. 168	54.016	90.844	0.491
clpC	Streptococcus pneumoniae Rx1	45.732	93.848	0.429
clpC	Streptococcus pneumoniae D39	45.732	93.848	0.429
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.847	89.7	0.429
clpC	Streptococcus thermophilus LMD-9	45.427	93.848	0.426
clpC	Streptococcus thermophilus LMG 18311	44.97	93.848	0.422
clpC	Streptococcus pneumoniae TIGR4	46.85	88.555	0.415
clpC	Streptococcus mutans UA159	46.216	88.841	0.411
clpA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	42.079	86.695	0.365