Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NP438_RS09530 Genome accession   NZ_CP101921
Coordinates   1971375..1972031 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain QA-1986 83     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1966375..1977031
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NP438_RS09500 (NP438_09500) dcyD 1967255..1968241 (+) 987 WP_001695857.1 D-cysteine desulfhydrase -
  NP438_RS09505 (NP438_09505) tcyL 1968256..1968924 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NP438_RS09510 (NP438_09510) tcyN 1968921..1969673 (+) 753 WP_094395986.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NP438_RS09515 (NP438_09515) sdiA 1969902..1970624 (+) 723 WP_032256217.1 transcriptional regulator SdiA -
  NP438_RS09520 (NP438_09520) yecF 1970692..1970916 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NP438_RS09525 (NP438_09525) yecU 1970903..1971079 (-) 177 WP_001696741.1 protein YecU -
  NP438_RS23060 - 1971162..1971233 (-) 72 Protein_1868 transcriptional regulator -
  NP438_RS09530 (NP438_09530) letA 1971375..1972031 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NP438_RS09535 (NP438_09535) uvrC 1972028..1973860 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  NP438_RS09540 (NP438_09540) pgsA 1973917..1974465 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NP438_RS09560 (NP438_09560) - 1975069..1976037 (+) 969 WP_074194686.1 IS5 family transposase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=612602 NP438_RS09530 WP_000611335.1 1971375..1972031(+) (letA) [Escherichia coli strain QA-1986 83]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=612602 NP438_RS09530 WP_000611335.1 1971375..1972031(+) (letA) [Escherichia coli strain QA-1986 83]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAAGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACTAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486