Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   EL263_RS07890 Genome accession   NZ_AP018938
Coordinates   1490416..1491093 (-) Length   225 a.a.
NCBI ID   WP_000548959.1    Uniprot ID   Q9S1K2
Organism   Streptococcus pneumoniae strain ATCC 49619     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1485416..1496093
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL263_RS07850 (SPAT_1501) - 1485577..1486206 (-) 630 WP_000762090.1 NAD(P)-dependent oxidoreductase -
  EL263_RS07855 (SPAT_1502) - 1486445..1486645 (+) 201 WP_001826938.1 hypothetical protein -
  EL263_RS07870 (SPAT_1503) - 1487076..1487216 (+) 141 WP_000422775.1 MazG-like protein -
  EL263_RS07875 - 1487223..1487399 (+) 177 WP_000166031.1 MazG-like protein -
  EL263_RS07880 (SPAT_1504) thrS 1487457..1489400 (+) 1944 WP_000608349.1 threonine--tRNA ligase -
  EL263_RS07885 (SPAT_1505) - 1489449..1490423 (-) 975 WP_000887957.1 HAMP domain-containing histidine kinase -
  EL263_RS07890 (SPAT_1506) braR 1490416..1491093 (-) 678 WP_000548959.1 response regulator transcription factor Regulator
  EL263_RS07895 (SPAT_1507) - 1491249..1492322 (+) 1074 WP_001273827.1 DUF2974 domain-containing protein -
  EL263_RS07900 (SPAT_1508) - 1492413..1492715 (-) 303 WP_000281600.1 hypothetical protein -
  EL263_RS07905 (SPAT_1509) - 1492784..1493221 (-) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  EL263_RS07910 (SPAT_1510) - 1493297..1494139 (-) 843 WP_000160958.1 metallophosphoesterase family protein -
  EL263_RS07915 (SPAT_1511) - 1494251..1494901 (+) 651 WP_000188506.1 metal-dependent transcriptional regulator -
  EL263_RS07925 (SPAT_1512) - 1495021..1495728 (+) 708 WP_000749107.1 nicotinamide mononucleotide transporter family protein -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25964.16 Da        Isoelectric Point: 5.1362

>NTDB_id=61240 EL263_RS07890 WP_000548959.1 1490416..1491093(-) (braR) [Streptococcus pneumoniae strain ATCC 49619]
MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=61240 EL263_RS07890 WP_000548959.1 1490416..1491093(-) (braR) [Streptococcus pneumoniae strain ATCC 49619]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGATTGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1K2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471
  vicR Streptococcus mutans UA159

35.319

100

0.369

Multiple sequence alignment