Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   NPX81_RS20330 Genome accession   NZ_CP101866
Coordinates   4168088..4170910 (+) Length   940 a.a.
NCBI ID   WP_040064530.1    Uniprot ID   -
Organism   Escherichia coli strain LP5-1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 4163088..4175910
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPX81_RS20305 (NPX81_20320) soxR 4164025..4164489 (-) 465 WP_000412428.1 redox-sensitive transcriptional activator SoxR -
  NPX81_RS20310 (NPX81_20325) soxS 4164575..4164898 (+) 324 WP_000019358.1 superoxide response transcriptional regulator SoxS -
  NPX81_RS20315 (NPX81_20330) pdeC 4164901..4166487 (-) 1587 WP_000019542.1 c-di-GMP phosphodiesterase PdeC -
  NPX81_RS20320 (NPX81_20335) yjcB 4166917..4167198 (+) 282 WP_040064531.1 YjcB family protein -
  NPX81_RS20325 (NPX81_20340) ssb 4167297..4167833 (-) 537 WP_000168305.1 single-stranded DNA-binding protein SSB1 Machinery gene
  NPX81_RS20330 (NPX81_20345) uvrA 4168088..4170910 (+) 2823 WP_040064530.1 excinuclease ABC subunit UvrA Machinery gene
  NPX81_RS20335 (NPX81_20350) yjbR 4170945..4171301 (-) 357 WP_000155657.1 MmcQ/YjbR family DNA-binding protein -
  NPX81_RS20340 (NPX81_20355) yjbQ 4171305..4171721 (-) 417 WP_000270372.1 secondary thiamine-phosphate synthase enzyme YjbQ -
  NPX81_RS20345 (NPX81_20360) aphA 4171832..4172467 (-) 636 Protein_3992 acid phosphatase AphA -
  NPX81_RS20350 (NPX81_20365) - 4172530..4173692 (+) 1163 WP_085947771.1 IS3-like element IS3 family transposase -
  NPX81_RS20355 (NPX81_20370) aphA 4173724..4173807 (-) 84 Protein_3994 acid phosphatase AphA -
  NPX81_RS20360 (NPX81_20375) - 4174209..4174431 (+) 223 Protein_3995 hypothetical protein -
  NPX81_RS20365 (NPX81_20380) - 4174461..4174712 (+) 252 WP_000275035.1 hypothetical protein -

Sequence

Protein


Download         Length: 940 a.a.        Molecular weight: 103850.55 Da        Isoelectric Point: 6.6067

>NTDB_id=612084 NPX81_RS20330 WP_040064530.1 4168088..4170910(+) (uvrA) [Escherichia coli strain LP5-1]
MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS
PAISIEQKSTSHNPRSTVGTITEIHDYLRLLFARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPIIKERKG
EHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVIDRFKVRDDLAQRLAESFETALELSGGTAVVADMDDE
KAEELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQNPELSLAGGAIRGWDRRNFYYFQM
LKSLAEHYKFDVEAPWGSLGANVHKVVLYGSGKENIEFKYMNDRGDTSIRRHPFEGVLHNMERRYKETESSAVREELAKF
ISNRPCASCEGTRLRREARHVFVENTPLPAISDMSIGHAMEFFNNLKLAGQRAKIAEKILKEIGDRLKFLVNVGLNYLTL
SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLGTLIHLRNLGNTVIVVEHDEDAIRAADHVIDI
GPGAGVHGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEVPKKRVPANPEKVLKLTGARGNNLKDVTLTLPVGLFTCITG
VSGSGKSTLINDTLFPIAQRQLNGATIAEPAPYRDIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPE
SRARGYTPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEAREFF
DAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYILDEPTTGLHFADIQQLLDVLHKLRD
QGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGEILVSGTPETVAECEASHTARFLKPML

Nucleotide


Download         Length: 2823 bp        

>NTDB_id=612084 NPX81_RS20330 WP_040064530.1 4168088..4170910(+) (uvrA) [Escherichia coli strain LP5-1]
ATGGATAAGATCGAAGTTCGGGGCGCCCGCACCCATAATCTCAAAAACATCAACCTCGTTATCCCCCGCGACAAGCTCAT
TGTCGTGACCGGGCTTTCGGGTTCTGGCAAATCCTCGCTCGCTTTCGACACCTTATATGCCGAAGGGCAGCGCCGTTACG
TTGAATCCCTTTCCGCCTACGCGCGGCAGTTTCTGTCACTGATGGAAAAGCCGGACGTCGATCATATTGAGGGGCTTTCT
CCTGCCATCTCAATTGAGCAGAAATCGACGTCTCATAACCCGCGTTCTACGGTGGGGACAATCACCGAAATCCACGACTA
TTTGCGTTTGTTGTTTGCCCGCGTTGGCGAGCCGCGCTGTCCGGACCACGACGTCCCGCTGGCGGCGCAAACCGTCAGCC
AGATGGTGGATAACGTGCTGTCGCAGCCGGAAGGCAAGCGTCTGATGCTGCTCGCGCCAATCATTAAAGAGCGCAAAGGC
GAACACACCAAAACGCTGGAGAACCTGGCAAGCCAGGGTTACATCCGCGCGCGCATTGATGGCGAAGTCTGCGATCTTTC
CGATCCGCCGAAACTGGAACTGCAAAAGAAACACACCATTGAAGTGGTTATCGATCGCTTCAAGGTGCGTGACGATCTCG
CCCAGCGTCTGGCTGAATCTTTTGAAACTGCGCTGGAGCTTTCCGGCGGTACGGCGGTCGTCGCCGATATGGACGACGAA
AAGGCAGAAGAGTTACTGTTCTCCGCGAACTTCGCCTGCCCGATTTGCGGTTACAGTATGCGCGAGCTGGAACCGCGCCT
GTTCTCGTTTAACAACCCGGCGGGTGCCTGCCCGACCTGTGACGGCCTCGGCGTACAGCAATATTTCGATCCTGACCGCG
TGATCCAGAACCCGGAGCTGTCGCTGGCGGGCGGCGCGATCCGTGGCTGGGATCGACGTAATTTCTATTACTTCCAGATG
CTGAAATCGCTGGCGGAACACTACAAGTTTGACGTGGAAGCGCCGTGGGGCAGCCTGGGCGCAAACGTGCATAAAGTGGT
GCTGTACGGCTCTGGTAAAGAAAATATCGAATTCAAATACATGAACGATCGTGGCGATACTTCCATTCGTCGTCATCCGT
TCGAAGGCGTGCTGCACAATATGGAGCGCCGTTATAAAGAGACGGAATCCAGCGCAGTACGTGAAGAGTTAGCTAAATTT
ATCAGCAACCGTCCGTGCGCCAGCTGTGAAGGGACACGTCTGCGCCGGGAAGCGCGCCATGTGTTCGTTGAGAATACGCC
GCTGCCCGCCATCTCCGACATGAGCATTGGTCATGCGATGGAATTCTTCAACAATCTGAAACTCGCCGGACAACGCGCGA
AGATTGCGGAAAAAATCCTTAAAGAGATTGGCGATCGCCTGAAATTCCTCGTTAACGTCGGGCTGAATTACCTGACGCTT
TCCCGCTCGGCAGAGACGCTTTCCGGCGGTGAAGCCCAGCGTATCCGTCTGGCAAGCCAGATTGGCGCGGGGCTGGTTGG
CGTTATGTACGTGCTCGATGAGCCGTCTATCGGCCTGCACCAGCGTGATAACGAGCGCCTGCTGGGAACGCTTATCCATC
TGCGCAATCTCGGTAATACCGTGATTGTGGTGGAGCACGACGAAGACGCGATTCGCGCGGCTGACCATGTGATCGATATC
GGTCCTGGTGCGGGTGTTCACGGCGGTGAAGTGGTCGCTGAAGGTCCGCTGGAAGCGATTATGGCGGTGCCGGAGTCGTT
AACCGGGCAGTACATGAGCGGCAAACGCAAAATTGAAGTGCCGAAGAAACGCGTTCCGGCGAATCCGGAAAAAGTGCTGA
AGCTGACCGGCGCACGCGGCAACAACCTGAAAGACGTGACGCTGACGCTGCCGGTGGGTCTGTTTACCTGCATTACCGGG
GTTTCAGGTTCCGGTAAATCGACGCTGATTAACGACACGCTGTTCCCGATTGCTCAACGCCAGTTGAACGGCGCGACCAT
CGCCGAACCGGCGCCGTATCGCGATATTCAGGGGCTGGAGCATTTCGATAAAGTGATCGATATCGACCAAAGCCCGATTG
GTCGTACTCCGCGTTCTAACCCGGCGACCTATACCGGCGTGTTTACGCCCGTGCGCGAACTGTTTGCGGGCGTACCGGAA
TCCCGTGCGCGCGGATATACGCCAGGACGTTTCAGCTTTAACGTCCGTGGCGGGCGCTGCGAAGCCTGTCAGGGCGACGG
TGTGATTAAAGTGGAGATGCACTTCCTGCCGGATATTTACGTACCGTGCGACCAGTGCAAAGGCAAACGCTATAACCGCG
AAACGCTGGAAATTAAGTACAAAGGCAAAACCATCCACGAAGTGCTGGATATGACCATCGAAGAGGCGCGTGAGTTCTTT
GATGCGGTGCCAGCTCTGGCGCGTAAGCTGCAAACGTTGATGGACGTTGGTCTGACGTACATTCGCCTGGGGCAGTCCGC
AACCACACTTTCTGGTGGTGAAGCCCAGCGCGTGAAGCTGGCGCGTGAGCTGTCAAAACGCGGCACCGGGCAGACGCTGT
ATATTCTCGACGAGCCGACCACCGGTCTGCACTTCGCCGATATTCAGCAACTCCTCGACGTGCTGCATAAACTGCGCGAT
CAGGGCAATACCATTGTGGTGATTGAGCACAATCTCGACGTGATCAAAACCGCTGACTGGATTGTCGACCTGGGACCAGA
AGGCGGCAGTGGCGGCGGCGAAATCCTCGTCTCCGGTACGCCAGAAACCGTCGCGGAGTGCGAAGCTTCGCATACGGCAC
GCTTCCTCAAGCCGATGCTGTAA

Domains

Predicted by InterProScan.

UvrA DNA-binding domain (UvrA_DNA-bind)

(290-399)

ABC transporter (ABC_tran)

(806-860)

UvrA interaction domain (UvrA_inter)

(130-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

57.052

100

0.572
  uvrA Streptococcus pneumoniae TIGR4

57.052

100

0.572
  uvrA Streptococcus pneumoniae D39

57.052

100

0.572