Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NPL72_RS09940 Genome accession   NZ_CP101705
Coordinates   2064636..2065292 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 035152     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2059636..2070292
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPL72_RS09910 (NPL72_09910) dcyD 2060515..2061501 (+) 987 WP_001128218.1 D-cysteine desulfhydrase -
  NPL72_RS09915 (NPL72_09915) tcyL 2061516..2062184 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NPL72_RS09920 (NPL72_09920) tcyN 2062181..2062933 (+) 753 WP_001273008.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NPL72_RS09925 (NPL72_09925) sdiA 2063163..2063885 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  NPL72_RS09930 (NPL72_09930) yecF 2063953..2064177 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NPL72_RS09935 (NPL72_09935) yecU 2064164..2064340 (-) 177 WP_000590347.1 protein YecU -
  NPL72_RS25065 - 2064423..2064494 (-) 72 Protein_1948 transcriptional regulator -
  NPL72_RS09940 (NPL72_09940) letA 2064636..2065292 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NPL72_RS09945 (NPL72_09945) uvrC 2065289..2067121 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  NPL72_RS09950 (NPL72_09950) pgsA 2067178..2067726 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NPL72_RS09970 (NPL72_09970) yecA 2068376..2069041 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=611642 NPL72_RS09940 WP_000611335.1 2064636..2065292(+) (letA) [Escherichia coli strain 035152]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=611642 NPL72_RS09940 WP_000611335.1 2064636..2065292(+) (letA) [Escherichia coli strain 035152]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486