Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NO473_RS01120 Genome accession   NZ_CP101666
Coordinates   237024..237680 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain M171-1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 232024..242680
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NO473_RS01090 dcyD 232903..233889 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  NO473_RS01095 tcyL 233904..234572 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NO473_RS01100 tcyN 234569..235321 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NO473_RS01105 sdiA 235551..236273 (+) 723 WP_024231281.1 transcriptional regulator SdiA -
  NO473_RS01110 yecF 236341..236565 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NO473_RS01115 yecU 236552..236728 (-) 177 WP_000590347.1 protein YecU -
  NO473_RS01120 letA 237024..237680 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NO473_RS01125 uvrC 237677..239509 (+) 1833 WP_046425971.1 excinuclease ABC subunit UvrC Machinery gene
  NO473_RS01130 pgsA 239566..240114 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NO473_RS01150 yecA 240763..241428 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=611527 NO473_RS01120 WP_000611328.1 237024..237680(+) (letA) [Escherichia coli strain M171-1]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=611527 NO473_RS01120 WP_000611328.1 237024..237680(+) (letA) [Escherichia coli strain M171-1]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACGAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482