Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   LA387_RS06015 Genome accession   NZ_CP084377
Coordinates   1161927..1162610 (-) Length   227 a.a.
NCBI ID   WP_004259224.1    Uniprot ID   A0A1I4FNQ8
Organism   Lactococcus garvieae strain Lg-Granada     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1156927..1167610
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LA387_RS05995 - 1157280..1158491 (-) 1212 WP_004259200.1 cysteine desulfurase -
  LA387_RS06000 sufD 1158491..1159747 (-) 1257 WP_019299087.1 Fe-S cluster assembly protein SufD -
  LA387_RS06005 sufC 1159819..1160589 (-) 771 WP_004259205.1 Fe-S cluster assembly ATPase SufC -
  LA387_RS06010 - 1160667..1161923 (-) 1257 WP_004259207.1 glycosyltransferase family 4 protein -
  LA387_RS06015 mecA 1161927..1162610 (-) 684 WP_004259224.1 adaptor protein MecA Regulator
  LA387_RS06020 - 1162854..1163762 (+) 909 WP_004259225.1 diacylglycerol/lipid kinase family protein -
  LA387_RS06025 rpoC 1163856..1167503 (-) 3648 WP_004259228.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 26239.38 Da        Isoelectric Point: 4.0202

>NTDB_id=610848 LA387_RS06015 WP_004259224.1 1161927..1162610(-) (mecA) [Lactococcus garvieae strain Lg-Granada]
MQYEEINEKTIKISLTFQDLVDHDVKLSDFFTNQSMVENLFYELVEELGLEERFSSGLLTFQIQPFPKGVNIIVTEENID
IDPNNLPDDPEEFEQLMTDFFGRVEDLKQNGGTMADTSTTETKETKVENKPDPDFVFYSLEFENMSQLLTAVKNVKIDAE
ESELYSYQDKFYLIILDNQKSKGKTAVSSMRARMLEYGQETVNSRETLQEYGEILINTRALEVLSKI

Nucleotide


Download         Length: 684 bp        

>NTDB_id=610848 LA387_RS06015 WP_004259224.1 1161927..1162610(-) (mecA) [Lactococcus garvieae strain Lg-Granada]
ATGCAATACGAAGAAATAAACGAAAAAACGATAAAGATTAGCCTAACCTTTCAAGATTTGGTTGATCATGATGTCAAACT
CTCTGATTTTTTTACTAACCAGTCAATGGTTGAAAATCTTTTTTATGAATTAGTAGAAGAGCTAGGACTTGAGGAAAGAT
TCTCATCAGGACTTTTAACTTTCCAAATTCAACCTTTCCCTAAAGGGGTGAATATCATTGTTACCGAGGAAAACATTGAT
ATTGATCCCAATAATCTCCCGGATGATCCTGAAGAATTTGAGCAGCTGATGACGGATTTCTTTGGGCGTGTGGAAGATTT
AAAACAAAATGGCGGAACAATGGCAGATACAAGTACAACTGAAACGAAAGAAACAAAAGTAGAAAATAAACCAGACCCAG
ATTTTGTCTTCTATTCTCTAGAATTTGAAAATATGTCTCAACTTTTGACAGCAGTAAAAAATGTTAAAATTGATGCAGAA
GAGTCTGAACTTTACAGTTACCAAGATAAGTTTTATTTGATTATTTTGGACAATCAAAAATCAAAAGGAAAAACAGCCGT
CAGTTCGATGCGTGCCCGAATGTTAGAATACGGCCAGGAAACGGTCAACAGTCGTGAAACCCTACAAGAATACGGCGAGA
TACTAATCAATACGCGTGCTTTGGAAGTTCTCTCAAAAATTTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1I4FNQ8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. cremoris KW2

54.661

100

0.568
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

54.077

100

0.555