Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   LA387_RS05550 Genome accession   NZ_CP084377
Coordinates   1085712..1087202 (-) Length   496 a.a.
NCBI ID   WP_004259093.1    Uniprot ID   -
Organism   Lactococcus garvieae strain Lg-Granada     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1080712..1092202
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LA387_RS05535 murD 1081506..1082867 (-) 1362 WP_004259085.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  LA387_RS05540 - 1083006..1083743 (-) 738 WP_004259087.1 amino acid ABC transporter ATP-binding protein -
  LA387_RS05545 - 1083744..1085315 (-) 1572 WP_004259090.1 ABC transporter permease subunit -
  LA387_RS05550 covS 1085712..1087202 (-) 1491 WP_004259093.1 HAMP domain-containing histidine kinase Regulator
  LA387_RS05555 covR 1087291..1087986 (-) 696 WP_004259096.1 response regulator transcription factor Regulator
  LA387_RS05560 - 1088088..1088639 (-) 552 WP_004259099.1 YceD family protein -
  LA387_RS05565 - 1088856..1089098 (-) 243 WP_003135050.1 type B 50S ribosomal protein L31 -
  LA387_RS05570 - 1089210..1091114 (-) 1905 WP_004259108.1 PTS fructose transporter subunit IIABC -
  LA387_RS05575 pfkB 1091129..1092055 (-) 927 WP_004259111.1 1-phosphofructokinase -

Sequence

Protein


Download         Length: 496 a.a.        Molecular weight: 56726.70 Da        Isoelectric Point: 5.1966

>NTDB_id=610843 LA387_RS05550 WP_004259093.1 1085712..1087202(-) (covS) [Lactococcus garvieae strain Lg-Granada]
MVKFFDSKKKKTESLPERKRSIMLRWAFANTIFCFITFTIFTVLVYQLTITTFINSEKEDMMKALDNVEQSLSQSESTLS
EENLANYLAYAKDYTASSQGKENELETLGSMIGSRKSFYVFDVGENLIYSTSSHGFPLKKDVGDGTHAVRTFGEYSGYLV
ERPVYSNKTGKLIGYVQAFYDMSYYYSVRTKLLIALIILEIIALFIAQFVGYFMASRYIKPLERLHDAITTRANNLKADF
KPVVIQTGDEIEELATVYNDMMIKLNDYVDQQKRFVSDVSHELRTPLAVLDGHLNLLNRWGKNDPEVLEESLQASIEEVS
TMRTMLEEMLALARLENIDFQDEDLICDPTEVSNFLKKNFLLIHADLSLTVENNLSPGRLAHIYPNHYEQGLKILIDNAI
KYSPKDRQEVKIHLEEDDKYIITTVEDHGYGISQEDLKHVFERFFRADKARNRDIGGTGLGLSIIQRIVENYDGDVSVTS
VVGEGSKFTLKIPKIK

Nucleotide


Download         Length: 1491 bp        

>NTDB_id=610843 LA387_RS05550 WP_004259093.1 1085712..1087202(-) (covS) [Lactococcus garvieae strain Lg-Granada]
ATGGTAAAATTTTTTGATTCGAAGAAGAAAAAAACAGAAAGTCTTCCCGAGCGTAAGCGAAGCATCATGCTACGTTGGGC
ATTTGCAAATACGATTTTTTGTTTTATTACCTTCACTATTTTTACAGTATTGGTTTACCAATTGACCATTACAACCTTCA
TCAATTCTGAAAAAGAGGATATGATGAAAGCTCTGGATAATGTTGAGCAAAGTTTGTCCCAATCGGAAAGCACACTGTCG
GAAGAAAATCTGGCGAATTATTTGGCTTATGCCAAAGACTATACAGCCTCCAGTCAGGGAAAAGAAAATGAGCTAGAAAC
ACTTGGAAGTATGATTGGCTCTAGGAAGTCCTTTTATGTTTTTGACGTCGGTGAAAATTTGATTTACTCGACCAGTTCGC
ATGGCTTCCCTCTAAAAAAAGACGTGGGGGATGGCACTCATGCTGTACGTACATTTGGTGAATATTCTGGTTATTTGGTC
GAACGACCAGTTTATTCTAATAAAACAGGTAAGCTGATTGGCTATGTGCAGGCTTTCTATGATATGAGTTATTATTATAG
CGTGCGAACAAAGTTACTGATTGCCCTGATTATCTTAGAGATTATTGCTCTCTTTATCGCTCAGTTTGTCGGTTATTTTA
TGGCGAGTCGTTACATCAAGCCTCTAGAACGGTTGCACGATGCAATTACTACACGTGCCAATAACTTGAAGGCGGATTTC
AAACCTGTAGTGATTCAAACAGGTGATGAAATTGAAGAACTGGCGACTGTTTATAATGACATGATGATCAAGCTTAACGA
TTATGTTGATCAGCAGAAACGTTTTGTTTCTGATGTTAGTCATGAGTTACGTACGCCACTTGCGGTTTTGGATGGTCATT
TGAATCTCTTGAACCGTTGGGGGAAAAACGATCCTGAGGTGCTTGAGGAGTCTTTACAGGCCAGTATAGAAGAAGTGAGT
ACGATGAGAACAATGTTGGAAGAGATGCTTGCATTGGCCCGTCTTGAAAACATTGATTTTCAAGATGAAGACCTTATCTG
TGATCCAACAGAAGTTTCTAATTTCCTTAAGAAAAACTTCCTACTTATCCATGCTGATTTAAGCTTAACTGTGGAAAATA
ACTTGTCACCGGGAAGATTGGCTCATATCTACCCGAACCATTATGAACAAGGCTTAAAAATTTTGATTGATAATGCTATA
AAATACTCGCCTAAAGATCGCCAAGAAGTGAAAATCCATCTAGAAGAAGATGATAAATACATTATCACTACGGTTGAGGA
TCATGGCTATGGCATTAGTCAGGAAGATTTAAAACATGTCTTTGAGCGTTTCTTCCGTGCTGATAAAGCGCGAAATCGGG
ATATAGGAGGCACGGGGCTTGGACTGTCTATTATTCAACGCATAGTGGAAAACTATGATGGGGATGTCAGTGTGACTTCT
GTTGTAGGTGAGGGATCGAAATTCACTTTAAAAATTCCTAAGATTAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(272-337)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(389-494)

ArlS sensor domain (ArlS_N)

(52-190)

HAMP domain (HAMP)

(214-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

55.734

100

0.558