Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   RES5_RS06230 Genome accession   NZ_CP084235
Coordinates   1246537..1247511 (+) Length   324 a.a.
NCBI ID   WP_037550626.1    Uniprot ID   -
Organism   Staphylococcus haemolyticus strain SE2.14     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1241537..1252511
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RES5_RS06195 (RES5_006195) rpmG 1241969..1242118 (+) 150 WP_011275661.1 50S ribosomal protein L33 -
  RES5_RS06200 (RES5_006200) - 1242355..1242891 (+) 537 WP_037550637.1 5-formyltetrahydrofolate cyclo-ligase -
  RES5_RS06205 (RES5_006205) - 1242907..1244364 (+) 1458 WP_161517199.1 rhomboid family intramembrane serine protease -
  RES5_RS06210 (RES5_006210) - 1244348..1244551 (+) 204 WP_037550632.1 YqgQ family protein -
  RES5_RS06215 (RES5_006215) - 1244548..1245534 (+) 987 WP_037550630.1 ROK family glucokinase -
  RES5_RS06220 (RES5_006220) - 1245534..1245857 (+) 324 WP_011275666.1 MTH1187 family thiamine-binding protein -
  RES5_RS06225 (RES5_006225) - 1245859..1246485 (+) 627 WP_037550628.1 MBL fold metallo-hydrolase -
  RES5_RS06230 (RES5_006230) comGA 1246537..1247511 (+) 975 WP_037550626.1 competence type IV pilus ATPase ComGA Machinery gene
  RES5_RS06235 (RES5_006235) comGB 1247483..1248547 (+) 1065 WP_161517201.1 competence type IV pilus assembly protein ComGB -
  RES5_RS06240 (RES5_006240) comGC 1248561..1248881 (+) 321 WP_011275670.1 competence type IV pilus major pilin ComGC Machinery gene
  RES5_RS06245 (RES5_006245) comGD 1248946..1249314 (+) 369 WP_226955309.1 competence type IV pilus minor pilin ComGD -
  RES5_RS06250 (RES5_006250) - 1249295..1249594 (+) 300 WP_053024491.1 hypothetical protein -
  RES5_RS11970 - 1249575..1249652 (+) 78 Protein_1205 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  RES5_RS06255 (RES5_006255) - 1249752..1250003 (+) 252 WP_226955311.1 hypothetical protein -
  RES5_RS06260 (RES5_006260) - 1250163..1250681 (+) 519 WP_085060036.1 shikimate kinase -
  RES5_RS06265 (RES5_006265) gcvT 1250870..1251961 (+) 1092 WP_053026662.1 glycine cleavage system aminomethyltransferase GcvT -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 37123.10 Da        Isoelectric Point: 8.4405

>NTDB_id=610233 RES5_RS06230 WP_037550626.1 1246537..1247511(+) (comGA) [Staphylococcus haemolyticus strain SE2.14]
MKLLFREIVNKAISKNASDIHFIPSVDEVHIKFRINDYLELYEIFNLDVYQKLLVFMKFKSGLDVSSQQSAQSGRYTYQS
KSTFYLRISTLPLSLGVESCVIRIIPQYFQAKKEYKEFNDFKHLVNKKQGLILLTGPTGSGKSTLMYQMVLHAYKELNLN
VITIENPVEQLLKGITQISINKKAGIDYISSFKAILRCDPDIILIGEIRDAEVAKCVIQASLSGHLVLSTMHSTNCRGAL
LRLLEMGISIQELTQSINIISNQRLITTTQNERRLICETIDKKQIQYFFEHEQTMPLNFNNLEQQLNLLSKEGTICEDTA
SKYF

Nucleotide


Download         Length: 975 bp        

>NTDB_id=610233 RES5_RS06230 WP_037550626.1 1246537..1247511(+) (comGA) [Staphylococcus haemolyticus strain SE2.14]
TTGAAACTATTATTCAGAGAGATAGTTAATAAAGCTATTTCAAAAAATGCGAGCGACATACATTTTATCCCTTCAGTTGA
TGAAGTTCATATTAAATTTAGAATTAATGATTATCTTGAACTTTATGAAATATTCAACTTAGATGTATATCAAAAATTAT
TAGTTTTTATGAAGTTCAAATCAGGTTTGGACGTTTCATCTCAACAATCCGCTCAAAGTGGTCGTTATACTTATCAATCT
AAATCTACTTTTTATTTACGGATTTCAACATTACCTTTGTCTTTAGGTGTAGAAAGTTGTGTAATTAGGATAATTCCTCA
ATATTTTCAAGCAAAAAAAGAATATAAAGAATTTAACGATTTTAAACACTTAGTAAATAAAAAACAGGGATTAATTCTAT
TAACTGGACCCACAGGATCCGGAAAAAGTACTCTGATGTATCAAATGGTTCTACATGCATATAAAGAATTAAATCTTAAT
GTTATCACTATCGAAAACCCAGTTGAGCAATTACTAAAAGGCATTACCCAAATATCAATAAATAAAAAGGCAGGTATAGA
CTACATAAGTTCATTTAAAGCTATATTAAGATGTGATCCTGATATTATTTTAATAGGTGAAATAAGAGACGCAGAAGTTG
CTAAATGTGTTATTCAAGCTAGTTTGAGTGGACACCTTGTATTATCAACCATGCATTCTACTAATTGTAGAGGTGCATTA
CTTCGATTACTTGAGATGGGAATTTCAATTCAAGAATTAACTCAATCTATCAATATCATTTCTAATCAAAGATTAATAAC
GACTACTCAGAATGAGCGTCGGTTAATTTGTGAAACAATAGATAAAAAGCAGATACAATATTTCTTCGAGCATGAACAAA
CAATGCCACTTAATTTTAATAATTTAGAACAGCAATTAAATTTATTATCTAAAGAAGGAACAATTTGTGAAGATACTGCA
AGTAAATATTTTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

65.944

99.691

0.657
  comGA Staphylococcus aureus N315

65.944

99.691

0.657