Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   I6G24_RS02395 Genome accession   NZ_CP084189
Coordinates   377803..379278 (+) Length   491 a.a.
NCBI ID   WP_023164352.1    Uniprot ID   -
Organism   Lactococcus lactis strain FDAARGOS_867     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 372803..384278
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G24_RS02360 (I6G24_02355) - 373063..373899 (+) 837 WP_023164354.1 metallophosphoesterase -
  I6G24_RS02365 (I6G24_02360) - 373960..374490 (+) 531 WP_003130764.1 CHAP domain-containing protein -
  I6G24_RS13850 - 374494..374625 (+) 132 WP_021722678.1 hypothetical protein -
  I6G24_RS02370 (I6G24_02365) - 374976..375338 (+) 363 WP_010906050.1 TIGR02328 family protein -
  I6G24_RS02375 (I6G24_02370) - 375420..375884 (+) 465 WP_003130761.1 hypothetical protein -
  I6G24_RS02380 (I6G24_02375) - 376040..376285 (+) 246 WP_003130760.1 type B 50S ribosomal protein L31 -
  I6G24_RS02385 (I6G24_02380) - 376416..376946 (+) 531 WP_023164353.1 DUF177 domain-containing protein -
  I6G24_RS02390 (I6G24_02385) covR 377102..377794 (+) 693 WP_003130756.1 response regulator transcription factor Regulator
  I6G24_RS02395 (I6G24_02390) covS 377803..379278 (+) 1476 WP_023164352.1 HAMP domain-containing histidine kinase Regulator
  I6G24_RS02400 (I6G24_02395) - 379461..380702 (+) 1242 WP_023164351.1 ammonium transporter -
  I6G24_RS02405 (I6G24_02400) - 380834..381175 (+) 342 WP_010906046.1 P-II family nitrogen regulator -
  I6G24_RS02410 (I6G24_02405) murD 381667..383019 (+) 1353 WP_003130748.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -

Sequence

Protein


Download         Length: 491 a.a.        Molecular weight: 56241.11 Da        Isoelectric Point: 4.8253

>NTDB_id=609934 I6G24_RS02395 WP_023164352.1 377803..379278(+) (covS) [Lactococcus lactis strain FDAARGOS_867]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQQLLTRSMDSVEEVLEKADAPL
NSSNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRHTFGFQNQANNEMKEIRGENPGYLVQRKII
SKSTGQVVGYLQAFYDTTTYHRISNLLLIVLLILEIVALIVAQLIGYFMANYFMKPLEKLYQGMQEMANDPTNDFEPIEI
QSGDEIEELAHVYNDMMLKMKTYLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLSLARLENVDLSSEELDCDVGKVCNRALKNFQLLHDDFEIVLDNRLIYPTHARISENHFEQGLRILLDNAAKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGISEEDINHLFERFFRADKARNREIGGTGLGLSILARLAENYQGEIEVNSELGLG
STFTLKFPKIK

Nucleotide


Download         Length: 1476 bp        

>NTDB_id=609934 I6G24_RS02395 WP_023164352.1 377803..379278(+) (covS) [Lactococcus lactis strain FDAARGOS_867]
ATGAAAAAATTATTTACTTTCAATAAGAAAAAAGAGACGGTAGAGGAAAGTTCGGCTAAGCGGTCTATCATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTTTGTTTGCTACTTTGACTTATCAATTGACAATCAGTTCTT
TTATTAAAGAAGAACAACAATTATTAACTCGCTCTATGGATAGTGTTGAGGAAGTCTTAGAAAAAGCAGATGCTCCTTTG
AATTCATCGAATTTGAACACATATATTGAAGCGACATCAAAGATTCAAAATGGTGAGTCTGAAGGAATGAGTTTGGGTAG
TATCATTGGGACACGGAAAGCATTTTATATTTATGACTTAAATCATAAATTATTGTATTCAACGAATCGACATACTTTTG
GTTTTCAGAATCAGGCTAATAATGAAATGAAAGAGATTCGGGGAGAAAATCCAGGTTATTTAGTTCAGAGAAAAATTATT
TCTAAGTCAACAGGACAAGTTGTGGGATACTTACAGGCTTTTTATGATACGACGACTTATCATCGAATTTCTAATCTTCT
TTTGATTGTCTTGTTAATTTTAGAAATTGTTGCCTTGATTGTCGCTCAGTTGATTGGTTATTTCATGGCTAATTACTTTA
TGAAACCATTGGAAAAACTTTATCAGGGCATGCAAGAAATGGCAAATGATCCAACAAATGATTTTGAACCGATTGAAATT
CAAAGTGGAGATGAAATCGAAGAGTTGGCTCATGTTTACAATGATATGATGTTGAAGATGAAGACATATCTTGAACAGCA
AAATCGCTTTGTTTCTGATGTTTCTCATGAATTAAGAACACCTTTAGCTGTCTTGGATGGACATATTAACTTGTTGAATC
GATGGGGGAAAAATGATCCAGAAGTATTAGATGAATCTTTGCAGGCAAGTTTAGATGAAGTTGATCGAATGAAGAAAATG
CTTGAGGAGATGTTGTCTCTTGCTCGCCTTGAAAATGTTGACTTATCAAGTGAAGAACTGGATTGTGATGTTGGAAAAGT
TTGTAATCGGGCCCTTAAGAATTTTCAGCTTTTGCATGATGATTTTGAAATAGTGCTTGATAACCGGCTTATTTATCCCA
CTCATGCGCGAATTTCAGAAAATCATTTTGAACAAGGTTTACGAATTCTGTTAGATAATGCTGCTAAATACTCTCCTGAT
GATCGTAAAGAAATCGTGATTACTGTTTCTGAGGATGAACAGTTTGTCATTACGAGTGTATCTGACAAAGGAATTGGAAT
TTCAGAAGAAGATATTAATCATCTTTTTGAGCGTTTCTTTAGAGCGGACAAGGCTCGCAATCGAGAAATTGGTGGAACTG
GTTTAGGTTTATCAATTTTAGCTCGATTGGCAGAAAATTATCAAGGGGAAATTGAGGTAAATTCAGAACTGGGTCTTGGT
TCAACTTTTACACTAAAATTCCCGAAAATAAAATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-489)

ArlS sensor domain (ArlS_N)

(54-185)

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)

HAMP domain (HAMP)

(208-257)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

99.593

100

0.996