Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NML17_RS13310 Genome accession   NZ_CP101274
Coordinates   2725448..2726104 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain EC21Z-014     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2720448..2731104
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NML17_RS13280 (NML17_13280) yecA 2721699..2722364 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  NML17_RS13300 (NML17_13300) pgsA 2723014..2723562 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NML17_RS13305 (NML17_13305) uvrC 2723619..2725451 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  NML17_RS13310 (NML17_13310) letA 2725448..2726104 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NML17_RS13315 (NML17_13315) yecU 2726400..2726576 (+) 177 WP_000590347.1 protein YecU -
  NML17_RS13320 (NML17_13320) yecF 2726563..2726787 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  NML17_RS13325 (NML17_13325) sdiA 2726854..2727576 (-) 723 WP_001154271.1 transcriptional regulator SdiA -
  NML17_RS13330 (NML17_13330) tcyN 2727806..2728558 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NML17_RS13335 (NML17_13335) tcyL 2728555..2729223 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  NML17_RS13340 (NML17_13340) dcyD 2729238..2730224 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=609882 NML17_RS13310 WP_000611335.1 2725448..2726104(-) (letA) [Escherichia coli strain EC21Z-014]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=609882 NML17_RS13310 WP_000611335.1 2725448..2726104(-) (letA) [Escherichia coli strain EC21Z-014]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486