Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NML18_RS09325 Genome accession   NZ_CP101269
Coordinates   1933804..1934460 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain EC21Z-048     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1928804..1939460
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NML18_RS09295 (NML18_09300) dcyD 1929684..1930670 (+) 987 WP_001128219.1 D-cysteine desulfhydrase -
  NML18_RS09300 (NML18_09305) tcyL 1930685..1931353 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NML18_RS09305 (NML18_09310) tcyN 1931350..1932102 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NML18_RS09310 (NML18_09315) sdiA 1932332..1933054 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  NML18_RS09315 (NML18_09320) yecF 1933121..1933345 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NML18_RS09320 (NML18_09325) yecU 1933332..1933508 (-) 177 WP_000590347.1 protein YecU -
  NML18_RS25475 - 1933591..1933662 (-) 72 Protein_1824 transcriptional regulator -
  NML18_RS09325 (NML18_09330) letA 1933804..1934460 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NML18_RS09330 (NML18_09335) uvrC 1934457..1936289 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  NML18_RS09335 (NML18_09340) pgsA 1936346..1936894 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NML18_RS09355 (NML18_09360) - 1937888..1938169 (+) 282 WP_071527557.1 hypothetical protein -
  NML18_RS09360 (NML18_09365) - 1938359..1938499 (-) 141 WP_000078916.1 Hok/Gef family protein -
  NML18_RS09365 (NML18_09370) - 1938691..1938951 (-) 261 WP_000488111.1 ogr/Delta-like zinc finger family protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=609808 NML18_RS09325 WP_000611335.1 1933804..1934460(+) (letA) [Escherichia coli strain EC21Z-048]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=609808 NML18_RS09325 WP_000611335.1 1933804..1934460(+) (letA) [Escherichia coli strain EC21Z-048]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486