Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NML27_RS10240 Genome accession   NZ_CP101197
Coordinates   2144644..2145300 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain EC21Z-151     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2139644..2150300
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NML27_RS10210 (NML27_10205) dcyD 2140524..2141510 (+) 987 WP_021561318.1 D-cysteine desulfhydrase -
  NML27_RS10215 (NML27_10210) tcyL 2141525..2142193 (+) 669 WP_001158231.1 cystine ABC transporter permease -
  NML27_RS10220 (NML27_10215) tcyN 2142190..2142942 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NML27_RS10225 (NML27_10220) sdiA 2143172..2143894 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  NML27_RS10230 (NML27_10225) yecF 2143961..2144185 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NML27_RS10235 (NML27_10230) yecU 2144172..2144348 (-) 177 WP_000590347.1 protein YecU -
  NML27_RS10240 (NML27_10235) letA 2144644..2145300 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NML27_RS10245 (NML27_10240) uvrC 2145297..2147129 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  NML27_RS10250 (NML27_10245) pgsA 2147186..2147734 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NML27_RS10270 (NML27_10265) - 2148441..2149172 (-) 732 WP_001595862.1 hypothetical protein -
  NML27_RS10275 (NML27_10270) - 2149253..2149936 (+) 684 Protein_2015 integrase arm-type DNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=609090 NML27_RS10240 WP_000611328.1 2144644..2145300(+) (letA) [Escherichia coli strain EC21Z-151]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=609090 NML27_RS10240 WP_000611328.1 2144644..2145300(+) (letA) [Escherichia coli strain EC21Z-151]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482