Detailed information NTG0060901

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: CYCME_RS11550
• Genome accession: NC_021917
• Coordinates: 2404180..2405550 (+)
• Length: 456 a.a.
• NCBI ID: WP_020933135.1
• Uniprot ID: S5U0B6
• Organism: Cycloclasticus zancles 78-ME
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 2399180..2410550

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CYCME_RS11535 (CYCME_2370)	sucD	2400399..2401271 (-)	873	WP_020933132.1	succinate--CoA ligase subunit alpha	-
CYCME_RS11540 (CYCME_2371)	sucC	2401286..2402446 (-)	1161	WP_020933133.1	ADP-forming succinate--CoA ligase subunit beta	-
CYCME_RS11545 (CYCME_2372)	-	2402542..2404173 (+)	1632	WP_020933134.1	sensor histidine kinase	-
CYCME_RS11550 (CYCME_2373)	pilR	2404180..2405550 (+)	1371	WP_020933135.1	sigma-54-dependent transcriptional regulator	Regulator
CYCME_RS13275 (CYCME_2374)	-	2405760..2406209 (+)	450	WP_041933069.1	pilin	-
CYCME_RS11560 (CYCME_2375)	-	2406280..2408211 (+)	1932	WP_020933137.1	tetratricopeptide repeat protein	-
CYCME_RS11565 (CYCME_2376)	nadA	2408389..2409477 (-)	1089	WP_020933138.1	quinolinate synthase NadA	-

Sequence

Protein

• Length: 456 a.a.
• Molecular weight: 50390.92 Da
• Isoelectric Point: 7.0243

>NTDB_id=60901 CYCME_RS11550 WP_020933135.1 2404180..2405550(+) (pilR) [Cycloclasticus zancles 78-ME]
MTQALALIVDDEPDILELLDITLSRMNISSKPAQDLAEAKRLLKTHHFDICLTDLQLPDGNGLELVKHIQKNTPNLPIAV
ITAFGSMDTAVKALKLGAFDFVSKPVDLKSLKSLVSSAIKINDTTEPVDRRSRDQLLGDSVMMANVRAKIAKLARSQAPI
YISGESGTGKELVAKLIHEKGPRSHQPFVPINCGAIPQELMESEFFGHKKGSFTGAIADKPGLFQTASGGTLFLDEVADL
PLHMQVKLLRAIQEKSIRPIGSDTEQPIDVRILSATHKNLPELVEQGNFRQDLYYRINVIELPLPPLRERAEDITQLAKH
ILQKLNAENNSPTKLTDTALKALAQYTFPGNVRELENILERAFTLCENGIIHQTDLQLPNNTKDAAAQTSGIKNPTQKTS
LPTQEAPLEDYLDSLEKEAITNALEKTRWNKTAAAKELGISFRALRYRLKKLGLND

Nucleotide

• Length: 1371 bp

>NTDB_id=60901 CYCME_RS11550 WP_020933135.1 2404180..2405550(+) (pilR) [Cycloclasticus zancles 78-ME]
ATGACTCAAGCGCTTGCCCTTATTGTTGACGACGAACCTGACATTCTCGAGTTACTTGATATCACCCTGTCTCGCATGAA
TATTTCGAGCAAACCCGCGCAAGACTTAGCCGAAGCAAAAAGATTACTAAAAACACACCACTTTGACATTTGCTTAACCG
ATCTTCAGCTGCCTGACGGAAATGGCCTTGAGCTTGTTAAGCATATTCAAAAAAACACTCCCAATCTACCCATTGCCGTT
ATTACCGCTTTTGGTAGTATGGACACTGCAGTCAAAGCACTAAAGCTTGGCGCTTTTGATTTCGTTTCCAAGCCTGTCGA
CCTGAAAAGCTTAAAAAGCCTCGTTAGCTCCGCTATTAAAATTAACGACACCACAGAACCCGTTGATAGGCGTAGTCGTG
ACCAACTATTAGGCGACTCCGTTATGATGGCAAACGTACGCGCAAAAATTGCCAAACTGGCTCGCAGCCAAGCACCGATC
TACATCAGCGGCGAGTCTGGAACCGGTAAAGAGTTGGTCGCCAAGCTAATTCATGAAAAAGGCCCACGATCGCATCAACC
TTTTGTGCCAATAAACTGTGGCGCTATTCCGCAGGAACTCATGGAGAGTGAGTTTTTTGGTCACAAAAAAGGCAGTTTCA
CCGGTGCCATTGCCGACAAACCCGGTCTTTTTCAAACGGCCAGTGGCGGCACCTTATTTTTAGATGAAGTTGCCGATTTA
CCACTGCATATGCAAGTCAAATTATTACGTGCAATTCAAGAAAAAAGCATTCGCCCCATTGGCAGCGATACAGAACAACC
CATTGACGTAAGAATATTAAGCGCCACCCATAAAAACCTTCCTGAGTTAGTTGAGCAAGGCAATTTTCGGCAAGACTTAT
ATTATAGAATTAATGTTATCGAACTACCGCTACCTCCTCTACGCGAGCGTGCAGAAGATATTACACAGCTGGCCAAGCAC
ATTTTACAAAAACTAAACGCCGAGAATAATAGCCCAACCAAGCTCACCGACACTGCGTTAAAAGCACTCGCTCAATACAC
TTTCCCCGGTAATGTGCGCGAATTAGAAAATATACTGGAACGCGCCTTCACTCTTTGTGAAAACGGTATTATTCATCAAA
CAGACTTACAACTGCCCAATAATACTAAAGACGCCGCCGCGCAGACTAGCGGTATTAAAAACCCAACACAAAAAACAAGC
CTCCCAACTCAAGAAGCACCGCTAGAAGACTATCTTGACAGCTTAGAGAAAGAAGCCATTACCAATGCCTTAGAAAAAAC
ACGCTGGAATAAAACAGCCGCCGCCAAAGAACTTGGCATCAGCTTTCGTGCGTTGCGTTATCGCTTAAAAAAATTAGGCC
TGAACGATTGA

Domains

Predicted by InterproScan.

• Bacterial regulatory protein, Fis family (HTH_8) (412-452)

• Response regulator receiver domain (Response_reg) (7-114)

• Sigma-54 interaction domain (Sigma54_activat) (137-302)

3D structure

• AlphaFold DB: S5U0B6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	59.524	100	0.603
pilR	Acinetobacter baumannii strain A118	53.648	100	0.548