Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NMD25_RS09045 Genome accession   NZ_CP101010
Coordinates   1877613..1878269 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain ET76     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1872613..1883269
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMD25_RS09010 (NMD25_08975) dcyD 1873493..1874479 (+) 987 WP_032234841.1 D-cysteine desulfhydrase -
  NMD25_RS09015 (NMD25_08980) tcyL 1874494..1875162 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NMD25_RS09020 (NMD25_08985) tcyN 1875159..1875911 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NMD25_RS09025 (NMD25_08990) sdiA 1876141..1876863 (+) 723 WP_001154265.1 transcriptional regulator SdiA -
  NMD25_RS09030 (NMD25_08995) yecF 1876930..1877154 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NMD25_RS09035 (NMD25_09000) yecU 1877141..1877317 (-) 177 WP_001307856.1 protein YecU -
  NMD25_RS09040 - 1877400..1877471 (-) 72 Protein_1762 transcriptional regulator -
  NMD25_RS09045 (NMD25_09005) letA 1877613..1878269 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NMD25_RS09050 (NMD25_09010) uvrC 1878266..1880098 (+) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  NMD25_RS09055 (NMD25_09015) pgsA 1880155..1880703 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NMD25_RS09075 (NMD25_09035) yecA 1881353..1882018 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=608668 NMD25_RS09045 WP_000611328.1 1877613..1878269(+) (letA) [Escherichia coli strain ET76]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=608668 NMD25_RS09045 WP_000611328.1 1877613..1878269(+) (letA) [Escherichia coli strain ET76]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482