Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NMD30_RS08880 Genome accession   NZ_CP100994
Coordinates   1838863..1839519 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain ET201     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1833863..1844519
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMD30_RS08845 (NMD30_08780) dcyD 1834742..1835728 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  NMD30_RS08850 (NMD30_08785) tcyL 1835743..1836411 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NMD30_RS08855 (NMD30_08790) tcyN 1836408..1837160 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NMD30_RS08860 (NMD30_08795) sdiA 1837390..1838112 (+) 723 WP_001154258.1 transcriptional regulator SdiA -
  NMD30_RS08865 (NMD30_08800) yecF 1838180..1838404 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NMD30_RS08870 (NMD30_08805) yecU 1838391..1838567 (-) 177 WP_001302050.1 protein YecU -
  NMD30_RS08875 - 1838605..1838721 (-) 117 WP_001302039.1 hypothetical protein -
  NMD30_RS08880 (NMD30_08810) letA 1838863..1839519 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NMD30_RS08885 (NMD30_08815) uvrC 1839516..1841348 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  NMD30_RS08890 (NMD30_08820) pgsA 1841405..1841953 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NMD30_RS08910 (NMD30_08840) yecA 1842602..1843267 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=608345 NMD30_RS08880 WP_000611335.1 1838863..1839519(+) (letA) [Escherichia coli strain ET201]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=608345 NMD30_RS08880 WP_000611335.1 1838863..1839519(+) (letA) [Escherichia coli strain ET201]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTTGGAGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACTAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
AATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGCCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486