Detailed information NTG0060828

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: KE3_RS05625
• Genome accession: NC_021900
• Coordinates: 1113095..1114324 (-)
• Length: 409 a.a.
• NCBI ID: WP_020916897.1
• Uniprot ID: A0AB33AMD1
• Organism: Streptococcus lutetiensis 033
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1108095..1119324

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KE3_RS05605 (KE3_1146)	-	1109323..1109991 (+)	669	WP_043895254.1	YoaK family protein	-
KE3_RS05610	mmuM	1110024..1110968 (-)	945	Protein_1067	homocysteine S-methyltransferase	-
KE3_RS05615	-	1110987..1112278 (-)	1292	Protein_1068	amino acid permease	-
KE3_RS05620 (KE3_1147)	yihA	1112491..1113084 (-)	594	WP_043895055.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
KE3_RS05625 (KE3_1148)	clpX	1113095..1114324 (-)	1230	WP_020916897.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
KE3_RS05635 (KE3_1150)	-	1114551..1115045 (-)	495	WP_020916898.1	dihydrofolate reductase	-
KE3_RS05640 (KE3_1151)	-	1115128..1115967 (-)	840	WP_020916899.1	thymidylate synthase	-
KE3_RS05645 (KE3_1152)	-	1116295..1117470 (+)	1176	WP_020916900.1	hydroxymethylglutaryl-CoA synthase	-
KE3_RS05650 (KE3_1153)	-	1117460..1118731 (+)	1272	WP_020916901.1	hydroxymethylglutaryl-CoA reductase, degradative	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45224.79 Da
• Isoelectric Point: 4.5119

>NTDB_id=60828 KE3_RS05625 WP_020916897.1 1113095..1114324(-) (clpX) [Streptococcus lutetiensis 033]
MVGNRTNDVKVYCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLAEVPKPKELLATLDEYVVGQER
AKRALAVAVYNHYKRVSFAESRDEEDVELQKSNILLIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQINTK
NILFIVGGAFDGIEDIVKQRLGEKVIGFGQNNRKIDEDASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLTTDDLVRI
LTEPRNALVKQYQTLLSYDGVELEFDEDALQAIANKAIERKTGARGLRSIIEETMMDIMFEIPSRVEVTKVRITKDAVEG
KDKPILEIA

Nucleotide

• Length: 1230 bp

>NTDB_id=60828 KE3_RS05625 WP_020916897.1 1113095..1114324(-) (clpX) [Streptococcus lutetiensis 033]
ATGGTTGGAAATCGAACAAATGATGTAAAAGTTTATTGCTCATTTTGTGGAAAAAGCCAAGACGAAGTAAAAAAAATCAT
TGCCGGAAATAACGTATTTATCTGTAATGAATGTGTGGCTTTATCCCAAGAAATTATTAAAGAGGAGTTAGCAGAAGAAG
TTCTCGCAGATTTGGCTGAAGTTCCAAAACCAAAAGAATTATTAGCAACCCTCGATGAATATGTTGTCGGTCAAGAACGC
GCTAAACGTGCCCTCGCAGTGGCTGTATACAACCACTACAAACGTGTTTCATTTGCCGAAAGTCGTGATGAAGAAGATGT
TGAATTGCAAAAATCTAACATCTTATTGATTGGACCAACTGGTTCAGGGAAAACTTTCCTTGCTCAAACCTTGGCGAAAA
GTTTAAACGTTCCATTTGCGATTGCTGATGCGACATCATTGACAGAAGCAGGATACGTTGGTGAAGACGTTGAAAATATC
CTTTTGAAACTTATTCAAGCAGCTGATTTTAATATTGAACGCGCAGAACGTGGTATCATCTACGTGGATGAAATTGATAA
AATTGCCAAAAAAGGTGAAAATGTCTCAATCACTCGTGATGTTTCAGGTGAAGGTGTTCAACAAGCTCTTCTTAAAATTA
TTGAAGGAACAGTTGCTAGCGTGCCACCACAAGGTGGTCGTAAACACCCGAACCAAGAAATGATTCAAATCAATACTAAG
AATATCCTTTTCATCGTTGGTGGTGCTTTTGACGGTATTGAAGATATTGTTAAACAACGTCTCGGTGAAAAAGTTATTGG
TTTTGGTCAAAATAACCGTAAGATCGATGAAGATGCTTCTTATATGCAAGAAATTATCTCGGAAGATATTCAGAAATTTG
GTTTAATTCCTGAATTTATCGGACGTTTGCCAGTCGTTGCTGCCCTTGAACAATTGACAACAGATGATTTGGTACGAATC
TTGACAGAACCTCGTAATGCCTTGGTTAAACAATACCAAACGCTTCTATCATATGATGGTGTTGAGTTGGAATTTGATGA
AGATGCCCTTCAAGCTATTGCTAATAAAGCAATCGAACGTAAGACAGGTGCACGTGGACTTCGTTCAATCATTGAAGAAA
CAATGATGGATATCATGTTTGAAATTCCAAGTCGTGTAGAGGTCACTAAAGTCCGTATTACAAAAGATGCCGTTGAAGGC
AAAGATAAACCAATTTTAGAGATTGCCTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-390)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.998	100	0.89
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.853	98.044	0.577