Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NMD35_RS09495 Genome accession   NZ_CP100973
Coordinates   1967826..1968482 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain ET300     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1962826..1973482
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMD35_RS09460 (NMD35_09400) dcyD 1963706..1964692 (+) 987 WP_001128238.1 D-cysteine desulfhydrase -
  NMD35_RS09465 (NMD35_09405) tcyL 1964707..1965375 (+) 669 WP_106490898.1 cystine ABC transporter permease -
  NMD35_RS09470 (NMD35_09410) tcyN 1965372..1966124 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NMD35_RS09475 (NMD35_09415) sdiA 1966354..1967076 (+) 723 WP_001154276.1 transcriptional regulator SdiA -
  NMD35_RS09480 (NMD35_09420) yecF 1967143..1967367 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NMD35_RS09485 (NMD35_09425) yecU 1967354..1967530 (-) 177 WP_000590347.1 protein YecU -
  NMD35_RS09490 - 1967613..1967684 (-) 72 Protein_1853 transcriptional regulator -
  NMD35_RS09495 (NMD35_09430) letA 1967826..1968482 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NMD35_RS09500 (NMD35_09435) uvrC 1968479..1970311 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  NMD35_RS09505 (NMD35_09440) pgsA 1970368..1970916 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NMD35_RS09525 (NMD35_09460) yecA 1971566..1972231 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=608024 NMD35_RS09495 WP_000611335.1 1967826..1968482(+) (letA) [Escherichia coli strain ET300]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=608024 NMD35_RS09495 WP_000611335.1 1967826..1968482(+) (letA) [Escherichia coli strain ET300]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGAGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAACGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTTAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCAGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486