Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NMD37_RS10210 Genome accession   NZ_CP100966
Coordinates   2132328..2132984 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain ET350     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2127328..2137984
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMD37_RS10180 (NMD37_10135) dcyD 2128207..2129193 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  NMD37_RS10185 (NMD37_10140) tcyL 2129208..2129876 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NMD37_RS10190 (NMD37_10145) tcyN 2129873..2130625 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NMD37_RS10195 (NMD37_10150) sdiA 2130855..2131577 (+) 723 WP_001154269.1 transcriptional regulator SdiA -
  NMD37_RS10200 (NMD37_10155) yecF 2131645..2131869 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NMD37_RS10205 (NMD37_10160) yecU 2131856..2132032 (-) 177 WP_000590344.1 protein YecU -
  NMD37_RS10210 (NMD37_10165) letA 2132328..2132984 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NMD37_RS10215 (NMD37_10170) uvrC 2132981..2134813 (+) 1833 WP_028132062.1 excinuclease ABC subunit UvrC Machinery gene
  NMD37_RS10220 (NMD37_10175) pgsA 2134870..2135418 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NMD37_RS10240 (NMD37_10195) - 2136112..2136852 (-) 741 WP_001721490.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=607941 NMD37_RS10210 WP_000611328.1 2132328..2132984(+) (letA) [Escherichia coli strain ET350]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=607941 NMD37_RS10210 WP_000611328.1 2132328..2132984(+) (letA) [Escherichia coli strain ET350]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482