Detailed information NTG0607858

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: LAZ98_RS18400
• Genome accession: NZ_CP083764
• Coordinates: 3603911..3605074 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain DMB07
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3598911..3610074

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LAZ98_RS18370 (LAZ98_18370)	-	3599176..3599595 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
LAZ98_RS18375 (LAZ98_18375)	comFC	3599669..3600358 (-)	690	WP_201741798.1	phosphoribosyltransferase family protein	Machinery gene
LAZ98_RS18380 (LAZ98_18380)	-	3600364..3600648 (-)	285	WP_003151389.1	late competence development ComFB family protein	-
LAZ98_RS18385 (LAZ98_18385)	comFA	3600706..3602091 (-)	1386	WP_104842867.1	DEAD/DEAH box helicase	Machinery gene
LAZ98_RS18390 (LAZ98_18390)	-	3602199..3603047 (-)	849	WP_003151387.1	DegV family protein	-
LAZ98_RS18395 (LAZ98_18395)	degU	3603145..3603834 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
LAZ98_RS18400 (LAZ98_18400)	degS	3603911..3605074 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
LAZ98_RS18405 (LAZ98_18405)	-	3605297..3605944 (+)	648	WP_060657503.1	YigZ family protein	-
LAZ98_RS18410 (LAZ98_18410)	-	3605949..3606980 (+)	1032	Protein_3582	LCP family protein	-
LAZ98_RS18415 (LAZ98_18415)	-	3607320..3609119 (-)	1800	WP_159354647.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=607858 LAZ98_RS18400 WP_007407484.1 3603911..3605074(-) (degS) [Bacillus velezensis strain DMB07]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=607858 LAZ98_RS18400 WP_007407484.1 3603911..3605074(-) (degS) [Bacillus velezensis strain DMB07]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TGTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATTATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951