Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NMD40_RS09845 Genome accession   NZ_CP100958
Coordinates   2007621..2008277 (+) Length   218 a.a.
NCBI ID   WP_000611338.1    Uniprot ID   -
Organism   Escherichia coli strain ET450     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2002621..2013277
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMD40_RS09815 (NMD40_09755) dcyD 2003500..2004486 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  NMD40_RS09820 (NMD40_09760) tcyL 2004501..2005169 (+) 669 WP_001682968.1 cystine ABC transporter permease -
  NMD40_RS09825 (NMD40_09765) tcyN 2005166..2005918 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NMD40_RS09830 (NMD40_09770) sdiA 2006148..2006870 (+) 723 WP_032266073.1 transcriptional regulator SdiA -
  NMD40_RS09835 (NMD40_09775) yecF 2006938..2007162 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NMD40_RS09840 (NMD40_09780) yecU 2007149..2007325 (-) 177 WP_001307856.1 protein YecU -
  NMD40_RS09845 (NMD40_09785) letA 2007621..2008277 (+) 657 WP_000611338.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NMD40_RS09850 (NMD40_09790) uvrC 2008274..2010106 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  NMD40_RS09855 (NMD40_09795) pgsA 2010163..2010711 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NMD40_RS09875 (NMD40_09815) - 2011407..2012147 (-) 741 Protein_1924 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23908.65 Da        Isoelectric Point: 6.9614

>NTDB_id=607778 NMD40_RS09845 WP_000611338.1 2007621..2008277(+) (letA) [Escherichia coli strain ET450]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNSVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=607778 NMD40_RS09845 WP_000611338.1 2007621..2008277(+) (letA) [Escherichia coli strain ET450]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATTCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.691

94.954

0.491
  letA Legionella pneumophila strain ERS1305867

51.691

94.954

0.491