Detailed information    

insolico Bioinformatically predicted

Overview

Name   comF   Type   Machinery gene
Locus tag   LA331_RS08660 Genome accession   NZ_CP083658
Coordinates   1744241..1744876 (+) Length   211 a.a.
NCBI ID   WP_005233718.1    Uniprot ID   N9MQD0
Organism   Acinetobacter variabilis strain FDAARGOS_1487     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1742209..1767418 1744241..1744876 within 0


Gene organization within MGE regions


Location: 1742209..1767418
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LA331_RS08655 (LA331_08655) recG 1742209..1744254 (+) 2046 WP_005233719.1 ATP-dependent DNA helicase RecG -
  LA331_RS08660 (LA331_08660) comF 1744241..1744876 (+) 636 WP_005233718.1 ComF family protein Machinery gene
  LA331_RS08665 (LA331_08665) - 1744878..1745279 (-) 402 WP_005233717.1 NUDIX hydrolase -
  LA331_RS08670 (LA331_08670) - 1745308..1745898 (-) 591 WP_034580768.1 TIGR00730 family Rossman fold protein -
  LA331_RS08675 (LA331_08675) - 1746051..1747064 (+) 1014 WP_005233715.1 CorA family divalent cation transporter -
  LA331_RS08680 (LA331_08680) - 1747412..1747702 (-) 291 WP_005233714.1 STAS domain-containing protein -
  LA331_RS08685 (LA331_08685) - 1747715..1748350 (-) 636 WP_005233712.1 MlaC/ttg2D family ABC transporter substrate-binding protein -
  LA331_RS08690 (LA331_08690) - 1748369..1749046 (-) 678 WP_005233710.1 outer membrane lipid asymmetry maintenance protein MlaD -
  LA331_RS08695 (LA331_08695) mlaE 1749046..1749825 (-) 780 WP_004786970.1 lipid asymmetry maintenance ABC transporter permease subunit MlaE -
  LA331_RS08700 (LA331_08700) - 1749822..1750640 (-) 819 WP_005233709.1 ABC transporter ATP-binding protein -
  LA331_RS08705 (LA331_08705) - 1750996..1752579 (-) 1584 WP_005080957.1 IS66-like element ISAba25 family transposase -
  LA331_RS08710 (LA331_08710) tnpB 1752654..1752989 (-) 336 WP_000618091.1 IS66 family insertion sequence element accessory protein TnpB -
  LA331_RS08715 (LA331_08715) - 1752986..1753369 (-) 384 WP_005233700.1 transposase -
  LA331_RS08720 (LA331_08720) - 1753546..1755354 (-) 1809 WP_005233699.1 DEAD/DEAH box helicase -
  LA331_RS08725 (LA331_08725) - 1755882..1756712 (-) 831 WP_005233698.1 inositol monophosphatase family protein -
  LA331_RS08730 (LA331_08730) dxs 1756827..1758737 (-) 1911 WP_005233697.1 1-deoxy-D-xylulose-5-phosphate synthase -
  LA331_RS08735 (LA331_08735) ribA 1759049..1759651 (+) 603 WP_004786979.1 GTP cyclohydrolase II -
  LA331_RS08740 (LA331_08740) hemN 1759773..1761146 (-) 1374 WP_005233695.1 oxygen-independent coproporphyrinogen III oxidase -
  LA331_RS08745 (LA331_08745) hemF 1761389..1762336 (+) 948 WP_005233694.1 oxygen-dependent coproporphyrinogen oxidase -
  LA331_RS08750 (LA331_08750) - 1762487..1762693 (+) 207 WP_005233693.1 hypothetical protein -
  LA331_RS08755 (LA331_08755) aroE 1762792..1763580 (+) 789 WP_005233692.1 shikimate dehydrogenase -
  LA331_RS08760 (LA331_08760) - 1763967..1765790 (+) 1824 WP_005233691.1 acyl-CoA dehydrogenase C-terminal domain-containing protein -
  LA331_RS08765 (LA331_08765) - 1766150..1766359 (+) 210 WP_004786992.1 cold-shock protein -
  LA331_RS08770 (LA331_08770) - 1766456..1767418 (-) 963 WP_005233690.1 IS30 family transposase -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 24440.66 Da        Isoelectric Point: 9.4181

>NTDB_id=607178 LA331_RS08660 WP_005233718.1 1744241..1744876(+) (comF) [Acinetobacter variabilis strain FDAARGOS_1487]
MPMFKLLQQGKLWLNRLQPCQLCQTDYQNLHSVCQDCWQQLPWAHQTIQRQEMQFQVACDYAYPMDRLIQLFKYEQKLHL
EPLLAGALLTLKFPKVSAVVPMPISTERLVERGYNQSLLLAKHVAKHLQVPVWQPIERLKQHSQKGLSRLERIEDIEAQF
RVTTSSKVRYRKVLIIDDVVTTGSSIRALSQQLEKLGCQQIYAACLAGAKL

Nucleotide


Download         Length: 636 bp        

>NTDB_id=607178 LA331_RS08660 WP_005233718.1 1744241..1744876(+) (comF) [Acinetobacter variabilis strain FDAARGOS_1487]
ATGCCTATGTTTAAGCTGTTACAACAGGGTAAACTCTGGCTGAATCGTTTACAGCCTTGTCAGCTGTGCCAGACAGATTA
TCAAAACCTGCATTCTGTCTGTCAGGATTGCTGGCAACAGTTACCTTGGGCACATCAGACCATTCAGCGTCAGGAAATGC
AGTTTCAGGTGGCGTGTGACTATGCCTACCCAATGGATCGCCTGATTCAATTATTTAAATATGAACAAAAGCTGCATCTG
GAACCTTTATTGGCAGGTGCATTACTGACCTTAAAATTTCCTAAAGTCAGTGCAGTGGTTCCTATGCCGATTTCAACCGA
ACGGCTGGTCGAACGTGGCTATAATCAATCCCTATTACTGGCCAAGCATGTTGCCAAACACTTACAAGTTCCCGTCTGGC
AGCCCATTGAACGACTCAAGCAACATTCACAAAAAGGTTTAAGCCGTCTGGAACGTATCGAAGACATTGAAGCCCAATTC
AGGGTCACTACCTCTTCAAAAGTTCGTTATCGTAAGGTTCTGATTATCGATGATGTGGTTACGACTGGCAGCTCGATTCG
AGCTTTAAGCCAGCAACTGGAAAAACTGGGCTGCCAGCAGATTTATGCCGCTTGTCTGGCAGGAGCCAAACTTTAA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(117-207)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB N9MQD0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comF Acinetobacter baumannii strain A118

61.353

98.104

0.602
  comF Acinetobacter baumannii D1279779

60.87

98.104

0.597