Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NMD48_RS09545 Genome accession   NZ_CP100930
Coordinates   1954695..1955351 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain ET670     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1949695..1960351
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMD48_RS09510 (NMD48_09455) dcyD 1950575..1951561 (+) 987 WP_370602218.1 D-cysteine desulfhydrase -
  NMD48_RS09515 (NMD48_09460) tcyL 1951576..1952244 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NMD48_RS09520 (NMD48_09465) tcyN 1952241..1952993 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NMD48_RS09525 (NMD48_09470) sdiA 1953223..1953945 (+) 723 WP_001154265.1 transcriptional regulator SdiA -
  NMD48_RS09530 (NMD48_09475) yecF 1954012..1954236 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NMD48_RS09535 (NMD48_09480) yecU 1954223..1954399 (-) 177 WP_000590344.1 protein YecU -
  NMD48_RS09540 - 1954437..1954553 (-) 117 WP_001302039.1 hypothetical protein -
  NMD48_RS09545 (NMD48_09485) letA 1954695..1955351 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NMD48_RS09550 (NMD48_09490) uvrC 1955348..1957180 (+) 1833 WP_370562235.1 excinuclease ABC subunit UvrC Machinery gene
  NMD48_RS09555 (NMD48_09495) pgsA 1957237..1957785 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NMD48_RS09575 (NMD48_09515) yecA 1958435..1959100 (+) 666 WP_370562237.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=607126 NMD48_RS09545 WP_000611328.1 1954695..1955351(+) (letA) [Escherichia coli strain ET670]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=607126 NMD48_RS09545 WP_000611328.1 1954695..1955351(+) (letA) [Escherichia coli strain ET670]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTTGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482