Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NMD50_RS10200 Genome accession   NZ_CP100922
Coordinates   2028262..2028918 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain ET734     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2023262..2033918
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMD50_RS10160 (NMD50_10125) dcyD 2023366..2024352 (+) 987 WP_001128238.1 D-cysteine desulfhydrase -
  NMD50_RS10165 (NMD50_10130) tcyL 2024367..2025008 (+) 642 WP_337235629.1 cystine ABC transporter permease -
  NMD50_RS10170 (NMD50_10135) - 2025445..2025446 (-) 2 WP_370602901.1 IS1 family transposase -
  NMD50_RS10175 (NMD50_10140) tcyN 2025808..2026560 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NMD50_RS10180 (NMD50_10145) sdiA 2026790..2027512 (+) 723 WP_001154276.1 transcriptional regulator SdiA -
  NMD50_RS10185 (NMD50_10150) yecF 2027579..2027803 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NMD50_RS10190 (NMD50_10155) yecU 2027790..2027966 (-) 177 WP_000590347.1 protein YecU -
  NMD50_RS10195 - 2028049..2028120 (-) 72 Protein_1992 transcriptional regulator -
  NMD50_RS10200 (NMD50_10160) letA 2028262..2028918 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NMD50_RS10205 (NMD50_10165) uvrC 2028915..2030747 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  NMD50_RS10210 (NMD50_10170) pgsA 2030804..2031352 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NMD50_RS10230 (NMD50_10190) yecA 2032002..2032667 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=606963 NMD50_RS10200 WP_000611335.1 2028262..2028918(+) (letA) [Escherichia coli strain ET734]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=606963 NMD50_RS10200 WP_000611335.1 2028262..2028918(+) (letA) [Escherichia coli strain ET734]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGAGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAACGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTTAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCAGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486