Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   LA346_RS06725 Genome accession   NZ_CP083627
Coordinates   1271432..1272121 (+) Length   229 a.a.
NCBI ID   WP_000518008.1    Uniprot ID   A0A0B7KUQ5
Organism   Streptococcus pneumoniae strain FDAARGOS_1508     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1266432..1277121
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LA346_RS06700 (LA346_06700) gpsB 1266529..1266870 (+) 342 WP_000200645.1 cell division regulator GpsB -
  LA346_RS06710 (LA346_06710) - 1267356..1268513 (+) 1158 WP_000711414.1 class I SAM-dependent RNA methyltransferase -
  LA346_RS06715 (LA346_06715) mapZ 1268526..1269920 (+) 1395 WP_000039255.1 mid-cell-anchored protein MapZ -
  LA346_RS06720 (LA346_06720) gndA 1269996..1271420 (+) 1425 WP_000158793.1 NADP-dependent phosphogluconate dehydrogenase -
  LA346_RS06725 (LA346_06725) covR 1271432..1272121 (+) 690 WP_000518008.1 response regulator transcription factor Regulator
  LA346_RS06730 (LA346_06730) cbpJ 1272220..1273218 (+) 999 WP_000771053.1 choline-binding protein CbpJ -
  LA346_RS06735 (LA346_06735) - 1273336..1274568 (-) 1233 WP_000765684.1 MFS transporter -
  LA346_RS06740 (LA346_06740) - 1274727..1275197 (-) 471 WP_001809487.1 lanthionine synthetase LanC family protein -
  LA346_RS06745 (LA346_06745) - 1275097..1275455 (-) 359 Protein_1296 lantibiotic-modifying protein -
  LA346_RS10860 - 1276118..1276285 (+) 168 Protein_1297 transposase -
  LA346_RS10865 - 1276325..1276447 (+) 123 Protein_1298 hypothetical protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26914.21 Da        Isoelectric Point: 6.9836

>NTDB_id=606846 LA346_RS06725 WP_000518008.1 1271432..1272121(+) (covR) [Streptococcus pneumoniae strain FDAARGOS_1508]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=606846 LA346_RS06725 WP_000518008.1 1271432..1272121(+) (covR) [Streptococcus pneumoniae strain FDAARGOS_1508]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTTTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCTTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCAATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7KUQ5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467