Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NLZ09_RS08960 Genome accession   NZ_CP100525
Coordinates   1860021..1860677 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain LH13-b     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1855021..1865677
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLZ09_RS08930 (NLZ09_08930) dcyD 1855901..1856887 (+) 987 WP_001128238.1 D-cysteine desulfhydrase -
  NLZ09_RS08935 (NLZ09_08935) tcyL 1856902..1857570 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NLZ09_RS08940 (NLZ09_08940) tcyN 1857567..1858319 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NLZ09_RS08945 (NLZ09_08945) sdiA 1858549..1859271 (+) 723 WP_001154276.1 transcriptional regulator SdiA -
  NLZ09_RS08950 (NLZ09_08950) yecF 1859338..1859562 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NLZ09_RS08955 (NLZ09_08955) yecU 1859549..1859725 (-) 177 WP_000590347.1 protein YecU -
  NLZ09_RS24140 - 1859808..1859879 (-) 72 Protein_1753 transcriptional regulator -
  NLZ09_RS08960 (NLZ09_08960) letA 1860021..1860677 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NLZ09_RS08965 (NLZ09_08965) uvrC 1860674..1862506 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  NLZ09_RS08970 (NLZ09_08970) pgsA 1862563..1863111 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NLZ09_RS08990 (NLZ09_08990) yecA 1863761..1864426 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=605701 NLZ09_RS08960 WP_000611335.1 1860021..1860677(+) (letA) [Escherichia coli strain LH13-b]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=605701 NLZ09_RS08960 WP_000611335.1 1860021..1860677(+) (letA) [Escherichia coli strain LH13-b]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGAGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAACGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTTAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCAGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486