Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NLZ13_RS11290 Genome accession   NZ_CP100500
Coordinates   2297551..2298207 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain LH50-c     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2292551..2303207
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLZ13_RS11255 (NLZ13_11255) dcyD 2292654..2293640 (+) 987 WP_001128238.1 D-cysteine desulfhydrase -
  NLZ13_RS11260 (NLZ13_11260) tcyL 2293655..2294323 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NLZ13_RS11265 (NLZ13_11265) tcyN 2294320..2295072 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NLZ13_RS11270 (NLZ13_11270) sdiA 2295302..2296024 (+) 723 WP_001152713.1 transcriptional regulator SdiA -
  NLZ13_RS11275 (NLZ13_11275) yecF 2296091..2296315 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NLZ13_RS11280 (NLZ13_11280) yecU 2296302..2296463 (-) 162 WP_143360770.1 protein YecU -
  NLZ13_RS29810 - 2297338..2297409 (-) 72 Protein_2225 transcriptional regulator -
  NLZ13_RS11290 (NLZ13_11290) letA 2297551..2298207 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NLZ13_RS11295 (NLZ13_11295) uvrC 2298204..2300036 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  NLZ13_RS11300 (NLZ13_11300) pgsA 2300093..2300641 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NLZ13_RS11320 (NLZ13_11320) yecA 2301291..2301956 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=605619 NLZ13_RS11290 WP_000611335.1 2297551..2298207(+) (letA) [Escherichia coli strain LH50-c]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=605619 NLZ13_RS11290 WP_000611335.1 2297551..2298207(+) (letA) [Escherichia coli strain LH50-c]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486