Detailed information NTG0605176

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: K3A98_RS13970
• Genome accession: NZ_CP083259
• Coordinates: 2805510..2806397 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143414.1
• Uniprot ID: A0A6B0AX73
• Organism: Staphylococcus aureus strain HL25274
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2800510..2811397

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K3A98_RS13940 (K3A98_002766)	-	2800517..2800605 (+)	89	Protein_2708	hypothetical protein	-
K3A98_RS13945 (K3A98_002767)	-	2800713..2801210 (-)	498	WP_001065267.1	glutathione peroxidase	-
K3A98_RS13950 (K3A98_002768)	-	2801220..2801480 (-)	261	WP_072468805.1	hypothetical protein	-
K3A98_RS13955 (K3A98_002769)	-	2801862..2801975 (-)	114	WP_078065515.1	hypothetical protein	-
K3A98_RS13960 (K3A98_002770)	-	2802650..2804650 (-)	2001	WP_000776728.1	ABC transporter permease	-
K3A98_RS13965 (K3A98_002771)	-	2804647..2805402 (-)	756	WP_000923762.1	ABC transporter ATP-binding protein	-
K3A98_RS13970 (K3A98_002772)	braS	2805510..2806397 (-)	888	WP_000143414.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
K3A98_RS13975 (K3A98_002773)	braR	2806408..2807073 (-)	666	WP_000697882.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
K3A98_RS13980 (K3A98_002774)	-	2807099..2807299 (-)	201	WP_000604724.1	hypothetical protein	-
K3A98_RS13985 (K3A98_002775)	-	2807497..2808921 (+)	1425	WP_031874997.1	alkaline phosphatase	-
K3A98_RS14500	-	2808981..2809082 (-)	102	WP_000731972.1	SE2200 family small protein	-
K3A98_RS13995 (K3A98_002777)	-	2809204..2809659 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
K3A98_RS14000 (K3A98_002778)	-	2809903..2810664 (-)	762	WP_000323454.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34073.33 Da
• Isoelectric Point: 5.6141

>NTDB_id=605176 K3A98_RS13970 WP_000143414.1 2805510..2806397(-) (braS) [Staphylococcus aureus strain HL25274]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKDDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSTGIGLFIVKQISNHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=605176 K3A98_RS13970 WP_000143414.1 2805510..2806397(-) (braS) [Staphylococcus aureus strain HL25274]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAGATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATAAACAATATTATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGAATCGGTATTAGTGAGGCAGACTTACCTAAA
ATATTCGACAAAGGTTATTCGGGGTATAATGGACAACGTCAAAGTAATTCAACTGGGATTGGCTTATTTATTGTAAAGCA
AATTTCAAATCACACTAATCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A6B0AX73

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.305	100	0.983