Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   K3A98_RS06490 Genome accession   NZ_CP083259
Coordinates   1264837..1265523 (+) Length   228 a.a.
NCBI ID   WP_072468915.1    Uniprot ID   A0A5F0HFN7
Organism   Staphylococcus aureus strain HL25274     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1259837..1270523
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K3A98_RS06455 (K3A98_001282) yqeH 1260364..1261464 (+) 1101 WP_001280146.1 ribosome biogenesis GTPase YqeH -
  K3A98_RS06460 (K3A98_001283) aroE 1261478..1262284 (+) 807 WP_000666750.1 shikimate dehydrogenase -
  K3A98_RS06465 (K3A98_001284) yhbY 1262288..1262578 (+) 291 WP_000955234.1 ribosome assembly RNA-binding protein YhbY -
  K3A98_RS06470 (K3A98_001285) nadD 1262581..1263150 (+) 570 WP_000725165.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  K3A98_RS06475 (K3A98_001286) yqeK 1263140..1263724 (+) 585 WP_001017837.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  K3A98_RS06480 (K3A98_001287) rsfS 1263725..1264078 (+) 354 WP_001088020.1 ribosome silencing factor -
  K3A98_RS06485 (K3A98_001288) - 1264081..1264797 (+) 717 WP_000084840.1 class I SAM-dependent DNA methyltransferase -
  K3A98_RS06490 (K3A98_001289) comEA 1264837..1265523 (+) 687 WP_072468915.1 ComEA family DNA-binding protein Machinery gene
  K3A98_RS06495 (K3A98_001290) - 1265615..1266076 (+) 462 WP_000439693.1 ComE operon protein 2 -
  K3A98_RS06500 (K3A98_001291) comEC 1266081..1268282 (+) 2202 WP_001622275.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  K3A98_RS06505 (K3A98_001292) holA 1268339..1269313 (+) 975 WP_001282573.1 DNA polymerase III subunit delta -
  K3A98_RS06510 (K3A98_001293) rpsT 1269358..1269609 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25812.41 Da        Isoelectric Point: 9.3305

>NTDB_id=605152 K3A98_RS06490 WP_072468915.1 1264837..1265523(+) (comEA) [Staphylococcus aureus strain HL25274]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRDFENKDTALKQSTSENSSLSKLEDVQAKDGDNSK
NKGPVYVDIKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQFGENSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=605152 K3A98_RS06490 WP_072468915.1 1264837..1265523(+) (comEA) [Staphylococcus aureus strain HL25274]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAGATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGCCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATATAAAAGGTGCTGTTAAACACCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAATTTGGAGAAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5F0HFN7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

96.476

99.561

0.961
  comEA Staphylococcus aureus N315

96.476

99.561

0.961