Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   NLY77_RS09945 Genome accession   NZ_CP100431
Coordinates   1980446..1981087 (-) Length   213 a.a.
NCBI ID   WP_024394813.1    Uniprot ID   -
Organism   Streptococcus suis strain 1521251     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1975446..1986087
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLY77_RS09920 (NLY77_09920) comFA/cflA 1975600..1976892 (-) 1293 WP_024394375.1 DEAD/DEAH box helicase Machinery gene
  NLY77_RS09925 (NLY77_09925) - 1976949..1977581 (+) 633 WP_024394374.1 YigZ family protein -
  NLY77_RS09930 (NLY77_09930) cysK 1977671..1978597 (+) 927 WP_029178437.1 cysteine synthase A -
  NLY77_RS09935 (NLY77_09935) - 1978623..1978994 (-) 372 WP_024394815.1 S1 RNA-binding domain-containing protein -
  NLY77_RS09940 (NLY77_09940) - 1978996..1980396 (-) 1401 WP_172008900.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  NLY77_RS09945 (NLY77_09945) vraR 1980446..1981087 (-) 642 WP_024394813.1 response regulator transcription factor Regulator
  NLY77_RS09950 (NLY77_09950) - 1981059..1982075 (-) 1017 WP_002937028.1 sensor histidine kinase -
  NLY77_RS09955 (NLY77_09955) liaF 1982072..1982731 (-) 660 WP_225533322.1 cell wall-active antibiotics response protein LiaF -
  NLY77_RS09960 (NLY77_09960) stkP 1983188..1985182 (-) 1995 WP_009909429.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  NLY77_RS09965 (NLY77_09965) - 1985182..1985919 (-) 738 WP_012774983.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23804.39 Da        Isoelectric Point: 4.8970

>NTDB_id=605138 NLY77_RS09945 WP_024394813.1 1980446..1981087(-) (vraR) [Streptococcus suis strain 1521251]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVIVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=605138 NLY77_RS09945 WP_024394813.1 1980446..1981087(-) (vraR) [Streptococcus suis strain 1521251]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTTCGTCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCATTAGAGGTTAAACCCGATGTTATAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACCCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTACCTAGATAATGAAAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGTTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCAGCCATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCCTTCATATCCTTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

55.072

97.183

0.535
  degU Bacillus subtilis subsp. subtilis str. 168

38.496

100

0.408