Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   NLY76_RS00360 Genome accession   NZ_CP100430
Coordinates   61218..63155 (+) Length   645 a.a.
NCBI ID   WP_044684329.1    Uniprot ID   -
Organism   Streptococcus suis strain LSS42     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 56218..68155
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLY76_RS00340 (NLY76_00340) - 56331..56954 (+) 624 WP_044769929.1 HAD-IA family hydrolase -
  NLY76_RS00345 (NLY76_00345) comR 57059..57958 (+) 900 WP_044686821.1 helix-turn-helix domain-containing protein Regulator
  NLY76_RS00350 (NLY76_00350) - 58166..59386 (+) 1221 WP_044769931.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  NLY76_RS00355 (NLY76_00355) - 59577..61100 (+) 1524 WP_044769932.1 quinol oxidase -
  NLY76_RS00360 (NLY76_00360) hexB 61218..63155 (+) 1938 WP_044684329.1 DNA mismatch repair endonuclease MutL Machinery gene
  NLY76_RS00365 (NLY76_00365) ruvA 63194..63784 (+) 591 WP_044684330.1 Holliday junction branch migration protein RuvA Machinery gene
  NLY76_RS00370 (NLY76_00370) - 64219..64788 (+) 570 WP_012774893.1 DNA-3-methyladenine glycosylase I -
  NLY76_RS00375 (NLY76_00375) cinA 64825..66006 (+) 1182 WP_044684331.1 competence/damage-inducible protein A Machinery gene
  NLY76_RS00380 (NLY76_00380) recA 66058..67209 (+) 1152 WP_024416946.1 recombinase RecA Machinery gene
  NLY76_RS00385 (NLY76_00385) spx 67445..67843 (+) 399 WP_002939362.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 645 a.a.        Molecular weight: 72850.10 Da        Isoelectric Point: 5.3018

>NTDB_id=604964 NLY76_RS00360 WP_044684329.1 61218..63155(+) (hexB) [Streptococcus suis strain LSS42]
MSHIIELPEILANQIAAGEVIERPASVVKELVENSIDAGASQIEISVEEAGLKMIQITDNGEGIAPDEVALALRRHATSK
IKNQSDLFRIRTLGFRGEALPSIASVSHMIIETATADSAHGLHLEAKGGVIEKEEPVSRPVGTQITVSDLFYNTPARLKY
VRSQQAELSHIVDVVNRLSLAHPEIAFALVNEGRELIRTAGTGKLRQAISGIYGIASAKKMVEIEAEDLDFQISGYVSLP
ELTRANRNYISIFINGRYIKNFLLNRAILEGYGSKLMVGRFPLAVISIEIDPYLADVNVHPTKQEVRISKEKELMTLIRE
AISQALKEQDLIPDALENLAQSSTRPKVKAEQGTLPLREPKIYYDTIKQDFFLKPDVVAEDVKPLEEDRQEIVESPVENK
PTSVQFAERQSVESEDQEHPNLSAKELAKLADKLDREGTSTFPELEYFGQMHGTYLFAQGKTGLYIIDQHAAQERVKYEY
YREKIGQVDNSAQQLLVPYIFEFPQNDALDLVHKMDALRQVGVNLEKYGANQFILREHPIWMKEEEIESGIYEMCDMLLL
TDQVSIKQYRAELAIMMSCKRSIKANHALDDYSARDLLRQLSYCQNPYNCPHGRPVLVHFSKSDMEKMFRRIQENHTSLR
ELGKY

Nucleotide


Download         Length: 1938 bp        

>NTDB_id=604964 NLY76_RS00360 WP_044684329.1 61218..63155(+) (hexB) [Streptococcus suis strain LSS42]
ATGTCACATATTATTGAACTACCAGAAATACTAGCCAACCAGATTGCGGCTGGTGAGGTCATTGAGCGACCAGCCAGTGT
GGTTAAGGAGTTGGTGGAAAATTCTATTGACGCAGGGGCTAGTCAGATTGAAATTAGTGTTGAAGAGGCTGGCCTCAAAA
TGATTCAAATTACGGATAACGGTGAGGGAATTGCCCCTGATGAAGTAGCGCTTGCCCTCCGCCGTCACGCCACCAGTAAG
ATAAAAAATCAATCGGATTTGTTTCGTATTCGCACCCTCGGTTTTCGTGGAGAAGCTCTGCCCTCCATTGCTTCTGTCAG
TCATATGATCATTGAGACAGCTACGGCAGACTCTGCACACGGACTTCATTTGGAGGCCAAAGGTGGTGTCATCGAGAAAG
AGGAGCCAGTTAGTCGTCCAGTTGGCACACAGATTACTGTTTCGGATTTATTTTACAATACCCCTGCTCGTCTCAAATAC
GTTCGCAGTCAACAGGCTGAATTATCACATATTGTTGATGTTGTAAATCGATTGAGCCTAGCTCATCCGGAGATAGCCTT
TGCCTTAGTAAACGAAGGAAGAGAATTAATTAGAACTGCAGGGACAGGGAAACTTCGTCAGGCAATTTCAGGGATTTATG
GGATTGCTTCCGCCAAAAAAATGGTTGAAATTGAGGCAGAAGATCTGGATTTTCAGATTTCAGGTTATGTTTCCTTGCCA
GAGTTGACTCGTGCCAACCGCAACTACATTTCCATTTTCATCAATGGTCGCTATATCAAGAATTTTTTGCTGAATCGAGC
GATTTTGGAAGGTTACGGCAGTAAGTTGATGGTTGGACGCTTTCCGTTGGCAGTGATTTCTATAGAAATTGACCCCTATC
TTGCTGATGTCAATGTGCATCCGACCAAGCAGGAAGTTCGCATCTCCAAGGAAAAAGAACTCATGACCTTGATTCGAGAG
GCGATTAGTCAAGCGCTTAAAGAGCAGGACTTGATACCAGATGCTCTTGAGAATTTAGCTCAGTCAAGTACTCGACCAAA
AGTAAAAGCAGAGCAAGGCACCTTACCACTCAGAGAGCCAAAAATCTATTATGATACGATTAAGCAAGACTTCTTCTTAA
AACCAGACGTGGTCGCTGAGGATGTCAAACCTCTCGAAGAGGATAGGCAAGAGATTGTTGAGTCGCCTGTCGAAAATAAA
CCTACATCTGTTCAATTTGCAGAACGTCAGTCGGTGGAATCAGAAGATCAGGAGCATCCTAATCTAAGCGCAAAAGAATT
GGCAAAACTGGCAGATAAATTAGACCGGGAGGGAACATCGACATTTCCAGAGTTAGAATATTTTGGTCAAATGCATGGGA
CGTATTTATTTGCGCAAGGCAAGACAGGACTTTATATCATTGACCAGCATGCCGCACAAGAGAGGGTCAAATACGAATAC
TACCGTGAGAAAATTGGACAGGTTGACAATTCAGCTCAACAGTTATTGGTGCCCTATATTTTTGAATTTCCGCAGAATGA
TGCCCTTGACCTCGTCCACAAAATGGATGCCCTTCGTCAAGTTGGTGTCAACTTGGAAAAATATGGAGCTAATCAATTTA
TTCTGCGTGAACATCCTATTTGGATGAAGGAAGAAGAGATTGAGTCTGGCATTTATGAGATGTGCGACATGTTGCTCTTG
ACGGATCAGGTGTCAATCAAGCAGTATCGGGCAGAACTGGCCATCATGATGTCTTGTAAACGGTCAATCAAGGCCAATCA
TGCTTTGGATGATTATTCGGCGCGTGATTTATTGAGACAATTGTCTTACTGCCAAAATCCCTATAACTGCCCGCACGGTC
GCCCAGTCTTAGTACATTTTAGTAAATCGGATATGGAAAAAATGTTCCGTCGCATTCAGGAAAATCACACGAGTTTGCGA
GAATTGGGCAAGTATTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(210-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

MutL C terminal dimerisation domain (MutL_C)

(447-589)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

72.308

100

0.729