Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   NLY35_RS04710 Genome accession   NZ_CP100418
Coordinates   927390..928616 (+) Length   408 a.a.
NCBI ID   WP_002934974.1    Uniprot ID   A0A0H3MZQ3
Organism   Streptococcus suis strain STC104     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 922390..933616
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLY35_RS04680 (NLY35_04680) - 923338..923673 (+) 336 WP_002934966.1 hypothetical protein -
  NLY35_RS04685 (NLY35_04685) - 923769..924728 (+) 960 WP_023370402.1 ROK family glucokinase -
  NLY35_RS04690 (NLY35_04690) - 924854..925132 (+) 279 WP_012775087.1 hypothetical protein -
  NLY35_RS04695 (NLY35_04695) - 925144..925446 (+) 303 WP_202847696.1 hypothetical protein -
  NLY35_RS04700 (NLY35_04700) - 925499..926338 (+) 840 WP_202847697.1 thymidylate synthase -
  NLY35_RS04705 (NLY35_04705) - 926680..927192 (+) 513 WP_044683343.1 dihydrofolate reductase -
  NLY35_RS04710 (NLY35_04710) clpX 927390..928616 (+) 1227 WP_002934974.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  NLY35_RS04715 (NLY35_04715) yihA 928670..929257 (+) 588 WP_002934975.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  NLY35_RS04720 (NLY35_04720) ndk 929280..929693 (+) 414 WP_002934976.1 nucleoside-diphosphate kinase -
  NLY35_RS04725 (NLY35_04725) lepA 929789..931621 (+) 1833 WP_002934977.1 translation elongation factor 4 -
  NLY35_RS04730 (NLY35_04730) - 931671..931853 (-) 183 WP_002934978.1 4-oxalocrotonate tautomerase -
  NLY35_RS04735 (NLY35_04735) - 931988..933295 (+) 1308 WP_002934980.1 excalibur calcium-binding domain-containing protein -
  NLY35_RS04740 (NLY35_04740) - 933357..933581 (+) 225 WP_002934981.1 hypothetical protein -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45318.84 Da        Isoelectric Point: 4.6382

>NTDB_id=604818 NLY35_RS04710 WP_002934974.1 927390..928616(+) (clpX) [Streptococcus suis strain STC104]
MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=604818 NLY35_RS04710 WP_002934974.1 927390..928616(+) (clpX) [Streptococcus suis strain STC104]
ATGGCTGTTAAGCATACACATGAGCTAATCTATTGCTCATTTTGCGGAAAAAATCAAGAAGAAGTTAAAAAAATTATCGC
AGGGAACAATGTCTTCATTTGTAATGAGTGCGTGGAACTAGCACAGGAAATCATTCGTGAGGAACTGGCAGAAGAAGTTT
TGACAGACTTAGCCGATACGCCAAAGCCACAAGAATTACTCAATATCCTGAACAACTATGTCATCGGACAGGATCGTGCA
AAACGTGCTTTAGCAGTAGCCGTTTACAACCACTACAAACGTATCAATTTCCAGGATAGCCGTGATGAGAACGATGTTGA
TTTGCAAAAGTCAAATATCCTTATGATTGGTCCGACTGGTTCAGGAAAAACCTTCCTAGCACAGACCTTGGCTAAAAGTT
TGAATGTCCCGTTTGCTATTGCTGATGCGACCGCTCTTACTGAGGCGGGTTATGTTGGTGAAGACGTAGAAAATATCCTC
CTCAAACTTTTGCAGGCTGCAGACTTTAACATCGACCGTGCAGAAAGAGGAATTATCTATGTGGATGAAATTGATAAAAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTCCAGCAAGCTCTCCTAAAAATTATCG
AGGGAACTGTGGCCAGCGTACCACCACAAGGCGGACGCAAACATCCAAACCAAGAAATGATTCACGTGGACACCAAAAAT
ATCCTGTTTATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAACAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTCGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTCGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGTATTTTG
ACGGAACCGAAGAATGCTCTTGTAAAACAATATCAGACACTCTTGTCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAAGCAATTGAACGTAAGACTGGCGCTCGTGGACTTCGTTCCATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGCCAAGATAACGTTAAACGTGTTCGTGTAACAAAAGCAGCAGTAGACGGTAAG
GAAAAACCTTTACTAGAAACTGCTTAA

Domains

Predicted by InterProScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MZQ3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

83.13

100

0.833
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.209

98.529

0.574