Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   NKZ65_RS02180 Genome accession   NZ_CP100332
Coordinates   423377..424018 (+) Length   213 a.a.
NCBI ID   WP_024394813.1    Uniprot ID   -
Organism   Streptococcus suis strain STC84     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 418377..429018
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NKZ65_RS02160 (NKZ65_02160) - 418545..419282 (+) 738 WP_012774983.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  NKZ65_RS02165 (NKZ65_02165) stkP 419282..421276 (+) 1995 WP_009909429.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  NKZ65_RS02170 (NKZ65_02170) liaF 421697..422392 (+) 696 WP_024394812.1 cell wall-active antibiotics response protein LiaF -
  NKZ65_RS02175 (NKZ65_02175) - 422389..423405 (+) 1017 WP_204101642.1 sensor histidine kinase -
  NKZ65_RS02180 (NKZ65_02180) vraR 423377..424018 (+) 642 WP_024394813.1 response regulator transcription factor Regulator
  NKZ65_RS02185 (NKZ65_02185) - 424068..425468 (+) 1401 WP_024394814.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  NKZ65_RS02190 (NKZ65_02190) - 425470..425841 (+) 372 WP_024394815.1 S1 RNA-binding domain-containing protein -
  NKZ65_RS02195 (NKZ65_02195) cysK 425867..426793 (-) 927 WP_012774985.1 cysteine synthase A -
  NKZ65_RS02200 (NKZ65_02200) - 426883..427515 (-) 633 WP_015646510.1 YigZ family protein -
  NKZ65_RS02205 (NKZ65_02205) comFA/cflA 427572..428864 (+) 1293 WP_024415030.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23804.39 Da        Isoelectric Point: 4.8970

>NTDB_id=604303 NKZ65_RS02180 WP_024394813.1 423377..424018(+) (vraR) [Streptococcus suis strain STC84]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVIVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=604303 NKZ65_RS02180 WP_024394813.1 423377..424018(+) (vraR) [Streptococcus suis strain STC84]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTTCGTCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCATTAGAGGTTAAACCCGATGTTATAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACCCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTACCTAGATAATGAAAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGTTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCAGCCATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCCTTCATATCCTTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

55.072

97.183

0.535
  degU Bacillus subtilis subsp. subtilis str. 168

38.496

100

0.408