Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   K8227_RS04615 Genome accession   NZ_CP082948
Coordinates   943532..944758 (+) Length   408 a.a.
NCBI ID   WP_002934974.1    Uniprot ID   G7SE29
Organism   Streptococcus suis strain SZ1908     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 938532..949758
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K8227_RS04580 (K8227_04575) - 939536..939871 (+) 336 WP_002934966.1 hypothetical protein -
  K8227_RS04585 (K8227_04580) - 939967..940926 (+) 960 WP_012775086.1 ROK family glucokinase -
  K8227_RS04590 (K8227_04585) - 941052..941330 (+) 279 WP_012775087.1 hypothetical protein -
  K8227_RS04595 (K8227_04590) - 941342..941644 (+) 303 WP_012775088.1 hypothetical protein -
  K8227_RS04600 (K8227_04595) - 941697..942536 (+) 840 WP_011922359.1 thymidylate synthase -
  K8227_RS04605 (K8227_04600) - 942822..943334 (+) 513 WP_014636390.1 dihydrofolate reductase -
  K8227_RS04610 (K8227_04605) - 943337..943510 (+) 174 WP_002934972.1 hypothetical protein -
  K8227_RS04615 (K8227_04610) clpX 943532..944758 (+) 1227 WP_002934974.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  K8227_RS04620 (K8227_04615) yihA 944814..945401 (+) 588 WP_012775089.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  K8227_RS04625 (K8227_04620) ndk 945424..945837 (+) 414 WP_012028095.1 nucleoside-diphosphate kinase -
  K8227_RS04630 (K8227_04625) - 945941..946612 (+) 672 WP_011922364.1 HIRAN domain-containing protein -
  K8227_RS04635 (K8227_04630) lepA 946894..948726 (+) 1833 WP_002943192.1 translation elongation factor 4 -
  K8227_RS04640 (K8227_04635) - 948776..948958 (-) 183 WP_002934978.1 4-oxalocrotonate tautomerase -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45318.84 Da        Isoelectric Point: 4.6382

>NTDB_id=603832 K8227_RS04615 WP_002934974.1 943532..944758(+) (clpX) [Streptococcus suis strain SZ1908]
MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=603832 K8227_RS04615 WP_002934974.1 943532..944758(+) (clpX) [Streptococcus suis strain SZ1908]
ATGGCTGTTAAGCATACACATGAGCTAATCTATTGCTCATTTTGCGGAAAAAATCAAGAAGAAGTTAAAAAAATTATCGC
AGGGAACAATGTCTTCATTTGTAATGAGTGCGTGGAACTAGCACAGGAAATCATTCGTGAGGAACTGGCAGAAGAAGTTT
TGACAGACTTGGCCGATACGCCAAAGCCACAAGAATTACTCAATATCCTGAACAACTACGTCATCGGACAGGATCGTGCA
AAACGTGCTTTAGCAGTAGCCGTTTACAACCACTACAAACGTATCAATTTCCAAGATAGCCGTGATGAGAACGATGTTGA
TTTGCAAAAATCAAATATCCTCATGATTGGCCCGACTGGTTCAGGAAAAACCTTCCTAGCTCAGACCTTGGCTAAAAGTT
TGAATGTCCCGTTTGCTATTGCTGATGCGACCGCTCTTACTGAGGCAGGTTATGTTGGTGAAGACGTAGAAAATATCCTC
CTCAAACTTTTGCAGGCTGCAGACTTTAACATCGACCGTGCAGAAAGAGGAATTATCTATGTAGATGAAATTGATAAGAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTCCAGCAAGCTCTCCTAAAAATTATCG
AGGGAACTGTGGCCAGCGTACCACCACAAGGCGGACGTAAACATCCAAACCAAGAAATGATTCACGTGGACACCAAAAAT
ATCCTGTTTATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAACAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTCGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTCGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGCATTTTG
ACGGAACCGAAGAATGCTCTTGTAAAACAATACCAGACACTCTTGTCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAAGCAATTGAACGTAAAACTGGTGCTCGTGGACTTCGCTCTATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGTCAAGATAACGTTAAACGCGTTCGTGTAACAAAAGCAGCAGTAGACGGTAAA
GAAAAGCCTTTACTAGAAACTGCATAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SE29

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

83.13

100

0.833
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.209

98.529

0.574