Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NHF43_RS00940 Genome accession   NZ_CP099752
Coordinates   185298..185954 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 806883-11-2019     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 180298..190954
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NHF43_RS00910 (NHF43_00910) dcyD 181178..182164 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  NHF43_RS00915 (NHF43_00915) tcyL 182179..182847 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NHF43_RS00920 (NHF43_00920) tcyN 182844..183596 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NHF43_RS00925 (NHF43_00925) sdiA 183826..184548 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  NHF43_RS00930 (NHF43_00930) yecF 184615..184839 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NHF43_RS00935 (NHF43_00935) yecU 184826..185002 (-) 177 WP_000590347.1 protein YecU -
  NHF43_RS23395 - 185085..185156 (-) 72 Protein_181 transcriptional regulator -
  NHF43_RS00940 (NHF43_00940) letA 185298..185954 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NHF43_RS00945 (NHF43_00945) uvrC 185951..187783 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  NHF43_RS00950 (NHF43_00950) pgsA 187840..188388 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NHF43_RS00970 (NHF43_00970) yecA 189038..189703 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=602647 NHF43_RS00940 WP_000611335.1 185298..185954(+) (letA) [Escherichia coli strain 806883-11-2019]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=602647 NHF43_RS00940 WP_000611335.1 185298..185954(+) (letA) [Escherichia coli strain 806883-11-2019]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486