Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   K8B76_RS01640 Genome accession   NZ_CP082820
Coordinates   327011..327700 (+) Length   229 a.a.
NCBI ID   WP_000518018.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain SCAID PHRX1-2021     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 322011..332700
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K8B76_RS01615 (K8B76_01615) gpsB 322108..322449 (+) 342 WP_000146529.1 cell division regulator GpsB -
  K8B76_RS01625 (K8B76_01625) - 322935..324092 (+) 1158 WP_000711371.1 class I SAM-dependent RNA methyltransferase -
  K8B76_RS01630 (K8B76_01630) mapZ 324105..325499 (+) 1395 WP_000039252.1 mid-cell-anchored protein MapZ -
  K8B76_RS01635 (K8B76_01635) gndA 325575..326999 (+) 1425 WP_000158768.1 NADP-dependent phosphogluconate dehydrogenase -
  K8B76_RS01640 (K8B76_01640) covR 327011..327700 (+) 690 WP_000518018.1 response regulator transcription factor Regulator
  K8B76_RS01645 (K8B76_01645) cbpC 327799..328821 (+) 1023 WP_000771083.1 choline-binding protein CbpC -
  K8B76_RS01650 (K8B76_01650) cbpJ 328840..329838 (+) 999 WP_000771144.1 choline-binding protein CbpJ -
  K8B76_RS01655 (K8B76_01655) - 329956..331188 (-) 1233 WP_000765691.1 MFS transporter -
  K8B76_RS01660 (K8B76_01660) - 331231..332106 (-) 876 WP_010963214.1 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26898.22 Da        Isoelectric Point: 6.9836

>NTDB_id=602522 K8B76_RS01640 WP_000518018.1 327011..327700(+) (covR) [Streptococcus pneumoniae strain SCAID PHRX1-2021]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=602522 K8B76_RS01640 WP_000518018.1 327011..327700(+) (covR) [Streptococcus pneumoniae strain SCAID PHRX1-2021]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATTTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACACGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACTGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463