Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NHF37_RS08970 Genome accession   NZ_CP099590
Coordinates   1875699..1876355 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain WG1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1870699..1881355
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NHF37_RS08940 (NHF37_08940) dcyD 1871578..1872564 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  NHF37_RS08945 (NHF37_08945) tcyL 1872579..1873247 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NHF37_RS08950 (NHF37_08950) tcyN 1873244..1873996 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NHF37_RS08955 (NHF37_08955) sdiA 1874226..1874948 (+) 723 WP_001152715.1 transcriptional regulator SdiA -
  NHF37_RS08960 (NHF37_08960) yecF 1875016..1875240 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NHF37_RS08965 (NHF37_08965) yecU 1875227..1875403 (-) 177 WP_000590347.1 protein YecU -
  NHF37_RS23270 - 1875486..1875557 (-) 72 Protein_1757 transcriptional regulator -
  NHF37_RS08970 (NHF37_08970) letA 1875699..1876355 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NHF37_RS08975 (NHF37_08975) uvrC 1876352..1878184 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  NHF37_RS08980 (NHF37_08980) pgsA 1878241..1878789 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NHF37_RS09000 (NHF37_09000) yecA 1879439..1880104 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=602392 NHF37_RS08970 WP_000611335.1 1875699..1876355(+) (letA) [Escherichia coli strain WG1]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=602392 NHF37_RS08970 WP_000611335.1 1875699..1876355(+) (letA) [Escherichia coli strain WG1]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486