Detailed information NTG0601221

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: NE421_RS02435
• Genome accession: NZ_CP098791
• Coordinates: 512424..513737 (+)
• Length: 437 a.a.
• NCBI ID: WP_001289250.1
• Uniprot ID: A3M1Y8
• Organism: Acinetobacter baumannii strain 280820
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 507424..518737

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NE421_RS02420 (NE421_02420)	-	507544..509775 (-)	2232	WP_031966617.1	TonB-dependent siderophore receptor	-
NE421_RS02425 (NE421_02425)	tig	510190..511524 (+)	1335	WP_001198432.1	trigger factor	-
NE421_RS02430 (NE421_02430)	clpP	511717..512322 (+)	606	WP_000289452.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	-
NE421_RS02435 (NE421_02435)	clpX	512424..513737 (+)	1314	WP_001289250.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
NE421_RS02440 (NE421_02440)	-	513885..514601 (+)	717	WP_001269731.1	DUF2846 domain-containing protein	-
NE421_RS02445 (NE421_02445)	-	514626..515180 (-)	555	WP_000155519.1	DUF2059 domain-containing protein	-
NE421_RS02450 (NE421_02450)	-	515322..516848 (-)	1527	WP_000207467.1	fumarate hydratase	-

Sequence

Protein

• Length: 437 a.a.
• Molecular weight: 48082.87 Da
• Isoelectric Point: 4.9985

>NTDB_id=601221 NE421_RS02435 WP_001289250.1 512424..513737(+) (clpX) [Acinetobacter baumannii strain 280820]
MSEHPQGQKHCSFCGKTQSEVGKLIAGEDAYICNECVDVCLDLVQTSQQVEAGDWASKALPKPHEIRAALDQYVIGQDLA
KKTLSVAVYNHYKRLKVGQSGHVSKDVEIAKSNILLIGPTGSGKTLLAQTLARLLDVPFAMADATTLTEAGYVGEDVENI
VQKLLQKADYDVEKAQKGIIYIDEIDKITRKSENPSITRDVSGEGVQQALLKMIEGTVASIPPQGGRKHPQQEFIQIDTS
NILFICGGAFAGLEKIVQQRQEKGGIGFTADVKNKDETKKLAELFRQVEPTDLVKFGLIPEFIGRLPVIATLEELDEEAL
MQILTEPKNALTRQYQYLFNMENVDLVFEDSALRAVAKRALERNTGARGLRSILENVLLETMYDLPSRTDVGTVFINEAV
INGEAEPVYKSERQPKEAVTHESVAKADLKVIDSKSA

Nucleotide

• Length: 1314 bp

>NTDB_id=601221 NE421_RS02435 WP_001289250.1 512424..513737(+) (clpX) [Acinetobacter baumannii strain 280820]
ATGTCCGAACATCCTCAAGGACAAAAACATTGTTCATTTTGCGGTAAAACGCAGTCTGAAGTCGGGAAACTGATTGCGGG
CGAGGACGCATATATTTGTAATGAGTGTGTAGATGTCTGCTTAGACCTTGTACAAACCAGCCAACAGGTTGAAGCAGGTG
ACTGGGCGAGCAAGGCATTGCCAAAACCACATGAAATACGTGCGGCGCTTGATCAATATGTGATTGGTCAGGATCTTGCC
AAAAAGACATTATCTGTTGCCGTTTATAACCATTATAAGCGTTTGAAAGTCGGGCAATCTGGTCATGTGTCTAAAGATGT
GGAAATTGCTAAAAGTAACATTCTACTGATTGGGCCTACCGGTTCAGGTAAAACATTACTTGCTCAAACATTGGCTCGTT
TGTTAGATGTGCCGTTTGCAATGGCAGATGCGACTACTTTGACTGAAGCGGGTTATGTTGGCGAAGACGTTGAAAATATC
GTACAAAAGCTTTTGCAAAAAGCAGATTACGATGTAGAAAAAGCTCAAAAGGGCATTATCTACATTGATGAAATCGACAA
GATTACTCGTAAATCTGAAAATCCATCAATTACGCGTGATGTGTCTGGTGAAGGTGTACAACAAGCTTTGCTTAAGATGA
TTGAAGGTACTGTAGCTTCAATTCCACCACAAGGTGGACGTAAACATCCGCAGCAAGAGTTCATTCAAATTGATACCTCA
AATATTCTATTTATTTGTGGTGGTGCATTTGCTGGACTGGAAAAAATTGTACAACAGCGTCAAGAGAAAGGCGGAATTGG
CTTTACGGCTGATGTTAAAAACAAAGATGAAACCAAAAAACTTGCTGAATTATTCCGTCAAGTTGAGCCAACTGATTTAG
TTAAATTTGGTTTAATTCCAGAATTCATTGGCCGTTTACCAGTGATTGCAACGCTTGAAGAGCTTGATGAAGAAGCGTTA
ATGCAAATTCTGACTGAACCGAAAAATGCATTAACTCGTCAGTATCAATACCTGTTCAACATGGAAAATGTTGACCTCGT
ATTTGAAGATTCAGCTTTACGTGCAGTGGCTAAGCGTGCGCTTGAGCGTAATACCGGAGCTCGTGGCCTACGTTCGATTT
TGGAAAATGTTCTACTTGAAACGATGTATGACTTGCCAAGCCGTACAGATGTAGGAACAGTTTTCATTAATGAAGCAGTC
ATTAATGGTGAAGCTGAACCTGTCTACAAGTCAGAACGTCAGCCTAAAGAAGCTGTAACACATGAAAGTGTTGCTAAGGC
AGATTTAAAAGTAATTGATTCGAAGTCTGCTTAG

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (315-390)

• ClpX C4-type zinc finger (zf-C4_ClpX) (9-45)

• AAA domain (Cdc48 subfamily) (AAA_2) (111-309)

3D structure

• AlphaFold DB: A3M1Y8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	59.453	91.991	0.547
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	57.426	92.449	0.531