Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   K6969_RS02695 Genome accession   NZ_CP082205
Coordinates   532323..533012 (+) Length   229 a.a.
NCBI ID   WP_012027645.1    Uniprot ID   -
Organism   Streptococcus suis strain AKJ18     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 527323..538012
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6969_RS02670 (K6969_02615) - 527649..528992 (+) 1344 WP_029174431.1 DEAD/DEAH box helicase -
  K6969_RS02675 (K6969_02620) - 529010..529246 (+) 237 WP_029174430.1 DUF4059 family protein -
  K6969_RS02680 (K6969_02625) trxB 529260..530177 (+) 918 WP_171942910.1 thioredoxin-disulfide reductase -
  K6969_RS02685 (K6969_02630) - 530187..530726 (+) 540 WP_029175279.1 YceD family protein -
  K6969_RS02690 (K6969_02635) gndA 530814..532241 (+) 1428 WP_171942911.1 NADP-dependent phosphogluconate dehydrogenase -
  K6969_RS02695 (K6969_02640) covR 532323..533012 (+) 690 WP_012027645.1 DNA-binding response regulator Regulator
  K6969_RS02700 (K6969_02645) - 533482..534612 (+) 1131 WP_171942866.1 AI-2E family transporter -
  K6969_RS02705 (K6969_02650) nrdR 534684..535175 (+) 492 WP_024417739.1 transcriptional regulator NrdR -
  K6969_RS02710 (K6969_02655) - 535162..536313 (+) 1152 WP_171942867.1 replication initiation/membrane attachment protein -
  K6969_RS02715 (K6969_02660) dnaI 536313..537212 (+) 900 WP_044760154.1 primosomal protein DnaI -
  K6969_RS02720 (K6969_02665) - 537209..537922 (+) 714 WP_321537461.1 NADPH-dependent oxidoreductase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26255.14 Da        Isoelectric Point: 5.3968

>NTDB_id=600037 K6969_RS02695 WP_012027645.1 532323..533012(+) (covR) [Streptococcus suis strain AKJ18]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=600037 K6969_RS02695 WP_012027645.1 532323..533012(+) (covR) [Streptococcus suis strain AKJ18]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTACAGAACTATTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAATTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432