Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   K6974_RS10130 Genome accession   NZ_CP082204
Coordinates   2019008..2019697 (-) Length   229 a.a.
NCBI ID   WP_012027645.1    Uniprot ID   -
Organism   Streptococcus suis strain FJSM5     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2014008..2024697
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6974_RS10110 - 2014728..2015234 (-) 507 WP_228477146.1 hypothetical protein -
  K6974_RS10115 (K6974_10000) - 2015546..2016628 (-) 1083 WP_172056393.1 hypothetical protein -
  K6974_RS10120 (K6974_10005) - 2016813..2017205 (-) 393 WP_172056394.1 hypothetical protein -
  K6974_RS10125 (K6974_10010) - 2017414..2018538 (-) 1125 WP_105112157.1 AI-2E family transporter -
  K6974_RS10130 (K6974_10015) covR 2019008..2019697 (-) 690 WP_012027645.1 DNA-binding response regulator Regulator
  K6974_RS10135 (K6974_10020) gndA 2019779..2021206 (-) 1428 WP_099778184.1 NADP-dependent phosphogluconate dehydrogenase -
  K6974_RS10140 (K6974_10025) - 2021303..2021842 (-) 540 WP_104930015.1 DUF177 domain-containing protein -
  K6974_RS10145 (K6974_10030) trxB 2021852..2022769 (-) 918 WP_029176114.1 thioredoxin-disulfide reductase -
  K6974_RS10150 (K6974_10035) - 2022783..2023007 (-) 225 WP_002936682.1 DUF4059 family protein -
  K6974_RS10155 (K6974_10040) - 2023025..2024368 (-) 1344 WP_099807187.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26255.14 Da        Isoelectric Point: 5.3968

>NTDB_id=600006 K6974_RS10130 WP_012027645.1 2019008..2019697(-) (covR) [Streptococcus suis strain FJSM5]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=600006 K6974_RS10130 WP_012027645.1 2019008..2019697(-) (covR) [Streptococcus suis strain FJSM5]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTACAGAACTATTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
TAGTGATTTAGTGGAGCAAATTTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAGGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432