Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   K6972_RS08270 Genome accession   NZ_CP082203
Coordinates   1679928..1680617 (-) Length   229 a.a.
NCBI ID   WP_012027645.1    Uniprot ID   -
Organism   Streptococcus suis strain NJ3     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1674928..1685617
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6972_RS08245 (K6972_08245) - 1675397..1676110 (-) 714 WP_044684119.1 NADPH-dependent oxidoreductase -
  K6972_RS08250 (K6972_08250) dnaI 1676107..1677006 (-) 900 WP_014636109.1 primosomal protein DnaI -
  K6972_RS08255 (K6972_08255) - 1677006..1678157 (-) 1152 WP_222812479.1 replication initiation/membrane attachment protein -
  K6972_RS08260 (K6972_08260) nrdR 1678144..1678635 (-) 492 WP_002938341.1 transcriptional regulator NrdR -
  K6972_RS08265 (K6972_08265) - 1678707..1679837 (-) 1131 WP_012027644.1 AI-2E family transporter -
  K6972_RS08270 (K6972_08270) covR 1679928..1680617 (-) 690 WP_012027645.1 DNA-binding response regulator Regulator
  K6972_RS08275 (K6972_08275) gndA 1680699..1682126 (-) 1428 WP_002942698.1 NADP-dependent phosphogluconate dehydrogenase -
  K6972_RS08280 (K6972_08280) - 1682223..1682762 (-) 540 WP_105119181.1 DUF177 domain-containing protein -
  K6972_RS08285 (K6972_08285) trxB 1682772..1683689 (-) 918 WP_014638520.1 thioredoxin-disulfide reductase -
  K6972_RS08290 (K6972_08290) - 1683703..1683927 (-) 225 WP_002936682.1 DUF4059 family protein -
  K6972_RS08295 (K6972_08295) - 1683945..1685288 (-) 1344 WP_222812480.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26255.14 Da        Isoelectric Point: 5.3968

>NTDB_id=599948 K6972_RS08270 WP_012027645.1 1679928..1680617(-) (covR) [Streptococcus suis strain NJ3]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=599948 K6972_RS08270 WP_012027645.1 1679928..1680617(-) (covR) [Streptococcus suis strain NJ3]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTACAGAACTGTTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGTAAGCAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGT
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTGCGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACGGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432