Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   K6976_RS08625 Genome accession   NZ_CP082202
Coordinates   1782563..1783252 (-) Length   229 a.a.
NCBI ID   WP_012027645.1    Uniprot ID   -
Organism   Streptococcus suis strain SS389     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1777563..1788252
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6976_RS08600 (K6976_08600) - 1778033..1778746 (-) 714 WP_222759280.1 NADPH-dependent oxidoreductase -
  K6976_RS08605 (K6976_08605) dnaI 1778743..1779642 (-) 900 WP_024382411.1 primosomal protein DnaI -
  K6976_RS08610 (K6976_08610) - 1779642..1780793 (-) 1152 WP_222366550.1 replication initiation/membrane attachment protein -
  K6976_RS08615 (K6976_08615) nrdR 1780780..1781271 (-) 492 WP_002938341.1 transcriptional regulator NrdR -
  K6976_RS08620 (K6976_08620) - 1781343..1782473 (-) 1131 WP_105119183.1 AI-2E family transporter -
  K6976_RS08625 (K6976_08625) covR 1782563..1783252 (-) 690 WP_012027645.1 DNA-binding response regulator Regulator
  K6976_RS08630 (K6976_08630) gndA 1783334..1784761 (-) 1428 WP_002942698.1 NADP-dependent phosphogluconate dehydrogenase -
  K6976_RS08635 (K6976_08635) - 1784858..1785397 (-) 540 WP_105120085.1 DUF177 domain-containing protein -
  K6976_RS08640 (K6976_08640) trxB 1785407..1786324 (-) 918 WP_002942687.1 thioredoxin-disulfide reductase -
  K6976_RS08645 (K6976_08645) - 1786338..1786562 (-) 225 WP_002936682.1 DUF4059 family protein -
  K6976_RS08650 (K6976_08650) - 1786580..1787923 (-) 1344 WP_024406634.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26255.14 Da        Isoelectric Point: 5.3968

>NTDB_id=599896 K6976_RS08625 WP_012027645.1 1782563..1783252(-) (covR) [Streptococcus suis strain SS389]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=599896 K6976_RS08625 WP_012027645.1 1782563..1783252(-) (covR) [Streptococcus suis strain SS389]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGTAAGGAATTGGCCACGGAACTGTTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGTAAGCAGGTTCACATGC
ATGCTGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACGGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432