Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   K6976_RS05555 Genome accession   NZ_CP082202
Coordinates   1112939..1114165 (-) Length   408 a.a.
NCBI ID   WP_002934974.1    Uniprot ID   G7SE29
Organism   Streptococcus suis strain SS389     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1107939..1119165
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6976_RS05530 (K6976_05530) - 1108253..1109566 (-) 1314 WP_170239690.1 excalibur calcium-binding domain-containing protein -
  K6976_RS05535 (K6976_05535) - 1109701..1109883 (+) 183 WP_002934978.1 4-oxalocrotonate tautomerase -
  K6976_RS05540 (K6976_05540) lepA 1109933..1111765 (-) 1833 WP_002943192.1 translation elongation factor 4 -
  K6976_RS05545 (K6976_05545) ndk 1111861..1112274 (-) 414 WP_015646859.1 nucleoside-diphosphate kinase -
  K6976_RS05550 (K6976_05550) yihA 1112297..1112884 (-) 588 WP_014638915.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  K6976_RS05555 (K6976_05555) clpX 1112939..1114165 (-) 1227 WP_002934974.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  K6976_RS05560 (K6976_05560) - 1114363..1114875 (-) 513 WP_105140179.1 dihydrofolate reductase -
  K6976_RS05565 (K6976_05565) - 1115050..1115889 (-) 840 WP_029171793.1 thymidylate synthase -
  K6976_RS05570 (K6976_05570) - 1115941..1116243 (-) 303 WP_029171794.1 hypothetical protein -
  K6976_RS05575 (K6976_05575) - 1116255..1116533 (-) 279 WP_002934968.1 hypothetical protein -
  K6976_RS05580 (K6976_05580) - 1116659..1117618 (-) 960 WP_029171795.1 ROK family glucokinase -
  K6976_RS05585 (K6976_05585) - 1117710..1118045 (-) 336 WP_029171796.1 hypothetical protein -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45318.84 Da        Isoelectric Point: 4.6382

>NTDB_id=599881 K6976_RS05555 WP_002934974.1 1112939..1114165(-) (clpX) [Streptococcus suis strain SS389]
MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=599881 K6976_RS05555 WP_002934974.1 1112939..1114165(-) (clpX) [Streptococcus suis strain SS389]
ATGGCTGTTAAGCATACACATGAGCTAATCTATTGCTCATTTTGCGGAAAAAATCAAGAAGAAGTTAAAAAAATTATCGC
TGGGAACAATGTCTTCATTTGTAATGAATGCGTGGAACTAGCACAGGAAATCATTCGTGAGGAACTGGCAGAAGAAGTTT
TGACAGACTTAGCCGATACGCCAAAGCCACAAGAATTACTCAATATCCTGAACAACTACGTCATCGGACAGGATCGTGCA
AAACGTGCTTTAGCAGTAGCCGTTTATAACCACTACAAACGTATCAATTTCCAGGATAGCCGTGATGAGAACGATGTTGA
TTTGCAAAAATCAAATATCCTTATGATTGGCCCGACTGGTTCAGGAAAAACCTTCCTAGCTCAGACCTTGGCTAAAAGTT
TGAATGTCCCGTTTGCTATTGCTGATGCGACCGCTCTTACTGAGGCGGGTTATGTTGGTGAAGACGTAGAAAATATCCTC
CTCAAACTTTTGCAGGCTGCAGACTTTAACATCGACCGTGCAGAAAGAGGAATTATCTATGTGGATGAAATTGATAAAAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTCCAGCAAGCTCTCTTAAAAATTATCG
AGGGAACTGTGGCCAGCGTACCACCACAAGGCGGACGCAAACATCCAAACCAAGAAATGATTCACGTGGACACCAAAAAT
ATCCTGTTCATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAACAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTCGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTCGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGCATTTTG
ACGGAACCAAAGAATGCTCTTGTAAAACAATACCAGACACTCTTATCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAAGCAATTGAACGTAAGACTGGTGCTCGTGGACTTCGCTCCATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGTCAAGATAACGTTAAACGTGTTCGTGTAACAAAAGCAGCAGTAGACGGTAAG
GAAAAGCCTCTACTAGAAACTGCATAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SE29

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

83.13

100

0.833
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.209

98.529

0.574