Detailed information NTG0599686

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: K6968_RS07760
• Genome accession: NZ_CP082198
• Coordinates: 1564927..1565976 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis strain Transconjugant cNJ3
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1559927..1570976

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6968_RS07740 (K6968_07740)	nadE	1560333..1561157 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
K6968_RS07745 (K6968_07745)	-	1562453..1562980 (-)	528	WP_012027591.1	VanZ family protein	-
K6968_RS07750 (K6968_07750)	rlmN	1562977..1564089 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
K6968_RS07755 (K6968_07755)	-	1564098..1564739 (-)	642	WP_012027595.1	YutD-like domain-containing protein	-
K6968_RS07760 (K6968_07760)	sepM	1564927..1565976 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
K6968_RS07765 (K6968_07765)	coaD	1565963..1566451 (-)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
K6968_RS07770 (K6968_07770)	rsmD	1566441..1566980 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
K6968_RS07775 (K6968_07775)	-	1567288..1568010 (-)	723	WP_012027598.1	lipoprotein	-
K6968_RS07780 (K6968_07780)	-	1568067..1568453 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
K6968_RS07785 (K6968_07785)	-	1568453..1568671 (-)	219	WP_004194736.1	YqgQ family protein	-
K6968_RS07790 (K6968_07790)	-	1568979..1569581 (-)	603	WP_012027601.1	response regulator transcription factor	-
K6968_RS07795 (K6968_07795)	-	1569578..1570672 (-)	1095	WP_012027602.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=599686 K6968_RS07760 WP_012775295.1 1564927..1565976(-) (sepM) [Streptococcus suis strain Transconjugant cNJ3]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=599686 K6968_RS07760 WP_012775295.1 1564927..1565976(-) (sepM) [Streptococcus suis strain Transconjugant cNJ3]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605