Detailed information NTG0059930

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: L897_RS03495
• Genome accession: NC_021807
• Coordinates: 693725..694954 (+)
• Length: 409 a.a.
• NCBI ID: WP_020833422.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes HSC5
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 688725..699954

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L897_RS03470 (L897_03595)	-	689341..690618 (-)	1278	WP_020833420.1	hydroxymethylglutaryl-CoA reductase, degradative	-
L897_RS03475 (L897_03600)	-	690605..691780 (-)	1176	WP_042361493.1	hydroxymethylglutaryl-CoA synthase	-
L897_RS03480 (L897_03605)	-	691989..692828 (+)	840	WP_010922172.1	thymidylate synthase	-
L897_RS03485 (L897_03610)	-	692908..693405 (+)	498	WP_002984955.1	dihydrofolate reductase	-
L897_RS09225 (L897_03615)	-	693425..693595 (+)	171	WP_002984950.1	hypothetical protein	-
L897_RS03495 (L897_03620)	clpX	693725..694954 (+)	1230	WP_020833422.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
L897_RS03500 (L897_03625)	yihA	694964..695563 (+)	600	WP_011184414.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
L897_RS03505 (L897_03630)	-	695711..696454 (+)	744	WP_002984942.1	hypothetical protein	-
L897_RS03510 (L897_03635)	-	696512..698611 (-)	2100	WP_020833423.1	AAA family ATPase	-
L897_RS03515 (L897_03640)	rpiA	698990..699673 (+)	684	WP_010922176.1	ribose-5-phosphate isomerase RpiA	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45018.46 Da
• Isoelectric Point: 4.5775

>NTDB_id=59930 L897_RS03495 WP_020833422.1 693725..694954(+) (clpX) [Streptococcus pyogenes HSC5]
MAGNRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=59930 L897_RS03495 WP_020833422.1 693725..694954(+) (clpX) [Streptococcus pyogenes HSC5]
ATGGCAGGAAATAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATCGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTAAACACATCAGATTTGATTCAAATT
TTGACAGAACCAAGAAATGCCCTGGTCAAGCAATATCAGGCTCTTCTTTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAACGTAAAACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CGATGTTAGACATCATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	89.242	100	0.892
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575